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    Jaundice (icterus)

    Jaundice (icterus) is a topic covered in the Diagnosaurus.

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    Emergency Central

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    DDx

    Hyperbilirubinemia

    Unconjugated (indirect bilirubin)

    • Increased production: hemolysis, hematoma, pulmonary infarction
    • Impaired uptake and storage: posthepatitis hyperbilirubinemia, Gilbert's syndrome, Crigler-Najjar syndrome, drugs

    Conjugated (direct bilirubin)

    • Biliary obstruction: choledocholithiasis, pancreatic tumor, biliary stricture, primary sclerosing cholangitis, biliary duct carcinoma
    • Hepatocellular damage or intrahepatic cholestasis: hepatitis (eg, alcoholic, viral), hepatic cirrhosis, biliary cirrhosis, drugs, sepsis, cholangitis, liver abscess, Budd-Chiari syndrome, infectious mononucleosis, spirochetal infection, infiltrative disease (tuberculosis, sarcoidosis, lymphoma), industrial toxins
    • Hereditary bilirubin excretion defect: Dubin-Johnson syndrome, Rotor's syndrome

    Other causes of yellow skin

    • Carotenemia (excessive beta-carotene ingestion, especially in hypothyroidism)

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    Last updated: December 1, 2014

    Citation

    Zeiger, Roni F.. "Jaundice (icterus)." Diagnosaurus, 4th ed., McGraw-Hill Education, 2014. Emergency Central, emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114695/all/Jaundice__icterus_.
    Zeiger RF. Jaundice (icterus). Diagnosaurus. 4th ed. McGraw-Hill Education; 2014. https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114695/all/Jaundice__icterus_. Accessed April 22, 2019.
    Zeiger, R. F. (2014). Jaundice (icterus). In Diagnosaurus. Available from https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114695/all/Jaundice__icterus_
    Zeiger RF. Jaundice (icterus) [Internet]. In: Diagnosaurus. McGraw-Hill Education; 2014. [cited 2019 April 22]. Available from: https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114695/all/Jaundice__icterus_.
    * Article titles in AMA citation format should be in sentence-case
    TY - ELEC T1 - Jaundice (icterus) ID - 114695 A1 - Zeiger,Roni F, Y1 - 2014/12/01/ BT - Diagnosaurus UR - https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114695/all/Jaundice__icterus_ PB - McGraw-Hill Education ET - 4 DB - Emergency Central DP - Unbound Medicine ER -