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Male hypogonadism

Male hypogonadism is a topic covered in the Diagnosaurus.

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Hypogonadotropic (low or normal LH)

  • Hypopituitarism, eg, pituitary adenoma
  • Cushing's syndrome
  • Hypothyroidism
  • Hyperprolactinemia
  • Hemochromatosis
  • Estrogen-secreting tumor (testicular, adrenal)
  • Idiopathic
  • GnRH agonist therapy, eg, leuprolide
  • Drugs: alcohol, ketoconazole, spironolactone, marijuana, prior androgens, phenytoin, cimetidine, intrathecal opioids
  • Anorexia nervosa
  • Cirrhosis
  • Serious illness or malnutrition
  • Kallmann syndrome
  • Prader-Willi syndrome
Hypergonadotropic (primary testicular failure; high LH)
  • Male climacteric (andropause or male menopause)
  • Klinefelter syndrome
  • Orchitis, eg, mumps, gonorrhea, tuberculosis, leprosy
  • Radiation therapy
  • Cancer chemotherapy
  • Autoimmune
  • Uremia
  • Testicular trauma or torsion
  • Lymphoma
  • Myotonic dystrophy
  • Androgen insensitivity
  • Idiopathic

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Last updated: December 1, 2014


Zeiger, Roni F.. "Male Hypogonadism." Diagnosaurus, 4th ed., McGraw-Hill Education, 2014. Emergency Central, emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114326/all/Male_hypogonadism.
Zeiger RF. Male hypogonadism. Diagnosaurus. 4th ed. McGraw-Hill Education; 2014. https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114326/all/Male_hypogonadism. Accessed April 24, 2019.
Zeiger, R. F. (2014). Male hypogonadism. In Diagnosaurus. Available from https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114326/all/Male_hypogonadism
Zeiger RF. Male Hypogonadism [Internet]. In: Diagnosaurus. McGraw-Hill Education; 2014. [cited 2019 April 24]. Available from: https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114326/all/Male_hypogonadism.
* Article titles in AMA citation format should be in sentence-case
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