Reperfusion Therapy, Cerebral



  • An ischemic cerebrovascular accident (CVA), or stroke, is sudden interruption of regional cerebral blood supply
  • Cerebral reperfusion therapy involves:
    • Intravenous (IV) thrombolysis with IV recombinant tissue-plasminogen activator (tPA), alteplase
    • Endovascular mechanical embolectomy with a stent retriever


  • Thrombotic CVA: Thrombosis from atherothrombotic lesion, hypercoagulable state, sludging
  • Embolic CVA: Acute obstruction by an embolus from elsewhere, such as cardiac mural thrombus, aortic plaque, prosthetic cardiac valve
  • Other occlusive events: Dissection, vasospasm

There's more to see -- the rest of this topic is available only to subscribers.