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OTHER INFORMATION REQUIRED FOR EFFECTIVE DRUG MONITORING

OTHER INFORMATION REQUIRED FOR EFFECTIVE DRUG MONITORING is a topic covered in the Guide to Diagnostic Tests.

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Reliability of the Analytic Method

The analytic sensitivity of the drug monitoring method must be adequate. For some drugs, plasma levels are in the nanogram per milliliter range. Example: Tricyclic antidepressants, digoxin.

The specificity of the method must be known, because the drug’s metabolites or other drugs may interfere. Interference by metabolites, which may or may not be pharmacologically active, is of particular concern in immunologic assay methods using antibodies to the parent drug.

The precision of the method must be known to assess whether changes in levels are caused by method imprecision or by clinical changes.

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Citation

McPhee, Stephen J., et al. "OTHER INFORMATION REQUIRED for EFFECTIVE DRUG MONITORING." Guide to Diagnostic Tests, 7th ed., McGraw-Hill Education, 2017. Emergency Central, emergency.unboundmedicine.com/emergency/view/GDT/619575/all/OTHER_INFORMATION_REQUIRED_FOR_EFFECTIVE_DRUG_MONITORING.
McPhee SJ, Lu CM, Nicoll D. OTHER INFORMATION REQUIRED FOR EFFECTIVE DRUG MONITORING. Guide to Diagnostic Tests. 7th ed. McGraw-Hill Education; 2017. https://emergency.unboundmedicine.com/emergency/view/GDT/619575/all/OTHER_INFORMATION_REQUIRED_FOR_EFFECTIVE_DRUG_MONITORING. Accessed April 24, 2019.
McPhee, S. J., Lu, C. M., & Nicoll, D. (2017). OTHER INFORMATION REQUIRED FOR EFFECTIVE DRUG MONITORING. In Guide to Diagnostic Tests. Available from https://emergency.unboundmedicine.com/emergency/view/GDT/619575/all/OTHER_INFORMATION_REQUIRED_FOR_EFFECTIVE_DRUG_MONITORING
McPhee SJ, Lu CM, Nicoll D. OTHER INFORMATION REQUIRED for EFFECTIVE DRUG MONITORING [Internet]. In: Guide to Diagnostic Tests. McGraw-Hill Education; 2017. [cited 2019 April 24]. Available from: https://emergency.unboundmedicine.com/emergency/view/GDT/619575/all/OTHER_INFORMATION_REQUIRED_FOR_EFFECTIVE_DRUG_MONITORING.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - OTHER INFORMATION REQUIRED FOR EFFECTIVE DRUG MONITORING ID - 619575 A1 - McPhee,Stephen J, AU - Lu,Chuanyi Mark, AU - Nicoll,Diana, BT - Guide to Diagnostic Tests UR - https://emergency.unboundmedicine.com/emergency/view/GDT/619575/all/OTHER_INFORMATION_REQUIRED_FOR_EFFECTIVE_DRUG_MONITORING PB - McGraw-Hill Education ET - 7 DB - Emergency Central DP - Unbound Medicine ER -