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Clostridium difficile

Clostridium difficile is a topic covered in the Guide to Diagnostic Tests.

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Organism

Clostridium difficile

Clostridium difficile is a gram-positive anaerobic rod. C. difficile produces 2 toxins: toxin A, which is an enterotoxin, and toxin B, which is a cytotoxin.

C. difficile has been found in stool in 15–25% of patients with antibiotic-associated diarrhea, 10% of patients treated with antibiotics who do not have diarrhea, and in 95% of patients with diarrhea associated with pseudomembranous colitis.

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Citation

McPhee, Stephen J., et al. "Clostridium Difficile." Guide to Diagnostic Tests, 7th ed., McGraw-Hill Education, 2017. Emergency Central, emergency.unboundmedicine.com/emergency/view/GDT/619354/all/Clostridium_difficile.
McPhee SJ, Lu CM, Nicoll D. Clostridium difficile. Guide to Diagnostic Tests. 7th ed. McGraw-Hill Education; 2017. https://emergency.unboundmedicine.com/emergency/view/GDT/619354/all/Clostridium_difficile. Accessed March 24, 2019.
McPhee, S. J., Lu, C. M., & Nicoll, D. (2017). Clostridium difficile. In Guide to Diagnostic Tests. Available from https://emergency.unboundmedicine.com/emergency/view/GDT/619354/all/Clostridium_difficile
McPhee SJ, Lu CM, Nicoll D. Clostridium Difficile [Internet]. In: Guide to Diagnostic Tests. McGraw-Hill Education; 2017. [cited 2019 March 24]. Available from: https://emergency.unboundmedicine.com/emergency/view/GDT/619354/all/Clostridium_difficile.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Clostridium difficile ID - 619354 A1 - McPhee,Stephen J, AU - Lu,Chuanyi Mark, AU - Nicoll,Diana, BT - Guide to Diagnostic Tests UR - https://emergency.unboundmedicine.com/emergency/view/GDT/619354/all/Clostridium_difficile PB - McGraw-Hill Education ET - 7 DB - Emergency Central DP - Unbound Medicine ER -