Diagnosaurus
Acute tubular necrosis
Etiology
- Toxins: NSAIDs, antibiotics, contrast, multiple myeloma, rhabdomyolysis, hemolysis, chemotherapy, hyperuricemia, cyclosporine
- Ischemia, e.g., prolonged prerenal azotemia
DDx
- Prerenal azotemia, eg, dehydration
- Postrenal azotemia, eg, benign prostatic hyperplasia
- Other renal causes of acute renal failure
- Acute glomerulonephritis: immune complex (eg, IgA nephropathy), pauci-immune (eg, Wegener’s granulomatosis), anti-GBM disease
- Acute interstitial nephritis: drugs (eg, β-lactams), infections (eg, Streptococcus), immune (eg, systemic lupus erythematosus)
See related DDx
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Citation
Zeiger, Roni F.. "Acute Tubular Necrosis." Diagnosaurus, 4th ed., McGraw-Hill Education, 2015. Emergency Central, emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114957/all/Acute_tubular_necrosis.
Zeiger RFR. Acute tubular necrosis. Diagnosaurus. McGraw-Hill Education; 2015. https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114957/all/Acute_tubular_necrosis. Accessed March 26, 2023.
Zeiger, R. F. (2015). Acute tubular necrosis. In Diagnosaurus (4th ed.). McGraw-Hill Education. https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114957/all/Acute_tubular_necrosis
Zeiger RFR. Acute Tubular Necrosis [Internet]. In: Diagnosaurus. McGraw-Hill Education; 2015. [cited 2023 March 26]. Available from: https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114957/all/Acute_tubular_necrosis.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Acute tubular necrosis
ID - 114957
A1 - Zeiger,Roni F,
BT - Diagnosaurus
UR - https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114957/all/Acute_tubular_necrosis
PB - McGraw-Hill Education
ET - 4
DB - Emergency Central
DP - Unbound Medicine
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