Peripheral neuropathy (polyneuropathy)
Etiology
Metabolic & Systemic
- Diabetes mellitus
- Alcoholism
- Uremia
- Thiamine deficiency
- Vitamin B12 deficiency
- Multiple myeloma
- Amyloidosis
- Cryoglobulinemia
- Hypothyroidism or hyperthyroidism
- Sarcoidosis
- Paraneoplastic syndrome, eg, lung cancer
- Neuropathy associated with critical illness
- Hansen’s disease (leprosy)
- HIV/AIDS
- Lyme disease
- Diphtheritic neuropathy
- Polyarteritis nodosa
- Rheumatoid arthritis
- Temporal (giant cell) arteritis
- Metals: lead, mercury, arsenic, thallium
- Drugs: isoniazid, phenytoin, pyridoxine, nitrofurantoin, vincristine
- Industrial agents or pesticides: acrylamide, organophosphates, hexacarbon solvents, methyl bromide, carbon disulfide
- Charcot-Marie-Tooth disease (hereditary motor and sensory neuropathy, HMSN type I & II)
- Porphyria
- Friedrich’s ataxia
- Dejerine-Sottas disease (HMSN type III)
- Refsum disease (HMSN type IV)
- Guillain-Barré syndrome
- Chronic inflammatory demyelinating polyneuropathy (CIDP)
- Porphyria
- Diphtheritic neuropathy
- Toxic neuropathy
- Poliomyelitis
- Periodic paralysis syndrome
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Last updated: December 1, 2014
Citation
Zeiger, Roni F.. "Peripheral Neuropathy (polyneuropathy)." Diagnosaurus, 4th ed., McGraw-Hill Education, 2014. Emergency Central, emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114834/all/Peripheral_neuropathy__polyneuropathy_.
Zeiger RFR. Peripheral neuropathy (polyneuropathy). Diagnosaurus. McGraw-Hill Education; 2014. https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114834/all/Peripheral_neuropathy__polyneuropathy_. Accessed November 24, 2024.
Zeiger, R. F. (2014). Peripheral neuropathy (polyneuropathy). In Diagnosaurus (4th ed.). McGraw-Hill Education. https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114834/all/Peripheral_neuropathy__polyneuropathy_
Zeiger RFR. Peripheral Neuropathy (polyneuropathy) [Internet]. In: Diagnosaurus. McGraw-Hill Education; 2014. [cited 2024 November 24]. Available from: https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114834/all/Peripheral_neuropathy__polyneuropathy_.
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