Diagnosaurus
PTT increased
Etiology
Congenital factor deficiencies
- Contact factors (no clinical bleeding)
- Factor XII (no clinical bleeding)
- Factor XI
- Factor IX (hemophilia B)
- Factor VIII (hemophilia A)
- Factor VIII (von Willebrand's disease)
- Factor I (afibrinogenemia)
Anticoagulants
- Factor VIII inhibitor (postpartum, idiopathic, or after factor VIII infusions)
- Lupus anticoagulant (no clinical bleeding)
- Heparin
- Warfarin (PT increased more than PTT)
Other
- Disseminated intravascular coagulation (PT & PTT increased)
- Liver disease (PT increased more than PTT)
- Vitamin K deficiency (PT increased more than PTT)
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Last updated: December 1, 2014
Citation
Zeiger, Roni F.. "PTT Increased." Diagnosaurus, 4th ed., McGraw-Hill Education, 2014. Emergency Central, emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114681/all/PTT_increased.
Zeiger RFR. PTT increased. Diagnosaurus. McGraw-Hill Education; 2014. https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114681/all/PTT_increased. Accessed October 31, 2025.
Zeiger, R. F. (2014). PTT increased. In Diagnosaurus (4th ed.). McGraw-Hill Education. https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114681/all/PTT_increased
Zeiger RFR. PTT Increased [Internet]. In: Diagnosaurus. McGraw-Hill Education; 2014. [cited 2025 October 31]. Available from: https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114681/all/PTT_increased.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - PTT increased
ID - 114681
A1 - Zeiger,Roni F,
Y1 - 2014/12/01/
BT - Diagnosaurus
UR - https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114681/all/PTT_increased
PB - McGraw-Hill Education
ET - 4
DB - Emergency Central
DP - Unbound Medicine
ER -
