Hemolytic anemia
Etiology
Coombs positive (immune)
- Autoimmune, drugs, infection, lymphoproliferative disease, Rh or ABO incompatibility
Coombs negative
- Intrinsic red cell disease
- Abnormal hemoglobin: sickle cell disease, thalassemia, methemoglobinemia
- Membrane defect: hereditary spherocytosis, hereditary elliptocytosis, paroxysmal nocturnal hemoglobinuria
- Enzyme defect: G6PD deficiency, pyruvate kinase deficiency
- Extrinsic disease
- Microangiopathic hemolytic anemia: thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, disseminated intravascular coagulation, prosthetic valve hemolysis, metastatic adenocarcinoma, vasculitis, malignant hypertension, HELLP syndrome
- Splenic sequestration
- Infection: malaria, Clostridium, Borrelia
- Burns
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Last updated: December 1, 2014
Citation
Zeiger, Roni F.. "Hemolytic Anemia." Diagnosaurus, 4th ed., McGraw-Hill Education, 2014. Emergency Central, emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114648/all/Hemolytic_anemia.
Zeiger RFR. Hemolytic anemia. Diagnosaurus. McGraw-Hill Education; 2014. https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114648/all/Hemolytic_anemia. Accessed December 9, 2024.
Zeiger, R. F. (2014). Hemolytic anemia. In Diagnosaurus (4th ed.). McGraw-Hill Education. https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114648/all/Hemolytic_anemia
Zeiger RFR. Hemolytic Anemia [Internet]. In: Diagnosaurus. McGraw-Hill Education; 2014. [cited 2024 December 09]. Available from: https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114648/all/Hemolytic_anemia.
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T1 - Hemolytic anemia
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A1 - Zeiger,Roni F,
Y1 - 2014/12/01/
BT - Diagnosaurus
UR - https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114648/all/Hemolytic_anemia
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