Folic acid deficiency
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Etiology
- Dietary deficiency
- Decreased absorption: tropical sprue, drugs (phenytoin, sulfasalazine, trimethoprim-sulfamethoxazole)
- Increased requirement: chronic hemolytic anemia, pregnancy, exfoliative skin disease
- Loss: dialysis
- Inhibition of reduction to active form: methotrexate
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Etiology
- Dietary deficiency
- Decreased absorption: tropical sprue, drugs (phenytoin, sulfasalazine, trimethoprim-sulfamethoxazole)
- Increased requirement: chronic hemolytic anemia, pregnancy, exfoliative skin disease
- Loss: dialysis
- Inhibition of reduction to active form: methotrexate
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