Splenomegaly
DDx
- Infections, eg, mononucleosis (Epstein-Barr virus), cytomegalovirus, acute HIV, endocarditis, histoplasmosis, malaria, schistosomiasis, leishmaniasis, filariasis
- Chronic hemolytic anemia
- Leukemia
- Lymphoma
- Extramedullary hematopoiesis, eg, myelofibrosis, marrow toxin
- Polycythemia vera
- Essential thrombocytosis
- Cirrhosis or noncirrhotic portal hypertension
- Congestive heart failure
- Immune thrombocytopenias
- Splenic vein thrombosis
- Rheumatoid arthritis (Felty’s syndrome)
- Systemic lupus erythematosus
- Sarcoidosis
- Wilson’s disease
- Amyloidosis
- Budd-Chiari syndrome
- Gaucher disease
- Niemann-Pick disease
- Splenic cysts, hemangiomas, hamartomas, fibromas
- Metastases, eg, melanoma
- Eosinophilic granuloma (Langerhans cell histiocytosis, histiocytosis X)
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Last updated: December 1, 2014
Citation
Zeiger, Roni F.. "Splenomegaly." Diagnosaurus, 4th ed., McGraw-Hill Education, 2014. Emergency Central, emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114508/all/Splenomegaly.
Zeiger RFR. Splenomegaly. Diagnosaurus. McGraw-Hill Education; 2014. https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114508/all/Splenomegaly. Accessed December 10, 2024.
Zeiger, R. F. (2014). Splenomegaly. In Diagnosaurus (4th ed.). McGraw-Hill Education. https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114508/all/Splenomegaly
Zeiger RFR. Splenomegaly [Internet]. In: Diagnosaurus. McGraw-Hill Education; 2014. [cited 2024 December 10]. Available from: https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114508/all/Splenomegaly.
* Article titles in AMA citation format should be in sentence-case
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T1 - Splenomegaly
ID - 114508
A1 - Zeiger,Roni F,
Y1 - 2014/12/01/
BT - Diagnosaurus
UR - https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114508/all/Splenomegaly
PB - McGraw-Hill Education
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DB - Emergency Central
DP - Unbound Medicine
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