Diagnosaurus
Splenomegaly
Splenomegaly is a topic covered in the Diagnosaurus.
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DDx
- Infections, eg, mononucleosis (Epstein-Barr virus), cytomegalovirus, acute HIV, endocarditis, histoplasmosis, malaria, schistosomiasis, leishmaniasis, filariasis
- Chronic hemolytic anemia
- Leukemia
- Lymphoma
- Extramedullary hematopoiesis, eg, myelofibrosis, marrow toxin
- Polycythemia vera
- Essential thrombocytosis
- Cirrhosis or noncirrhotic portal hypertension
- Congestive heart failure
- Immune thrombocytopenias
- Splenic vein thrombosis
- Rheumatoid arthritis (Felty’s syndrome)
- Systemic lupus erythematosus
- Sarcoidosis
- Wilson’s disease
- Amyloidosis
- Budd-Chiari syndrome
- Gaucher disease
- Niemann-Pick disease
- Splenic cysts, hemangiomas, hamartomas, fibromas
- Metastases, eg, melanoma
- Eosinophilic granuloma (Langerhans cell histiocytosis, histiocytosis X)
-- To view the remaining sections of this topic, please log in or purchase a subscription --
DDx
- Infections, eg, mononucleosis (Epstein-Barr virus), cytomegalovirus, acute HIV, endocarditis, histoplasmosis, malaria, schistosomiasis, leishmaniasis, filariasis
- Chronic hemolytic anemia
- Leukemia
- Lymphoma
- Extramedullary hematopoiesis, eg, myelofibrosis, marrow toxin
- Polycythemia vera
- Essential thrombocytosis
- Cirrhosis or noncirrhotic portal hypertension
- Congestive heart failure
- Immune thrombocytopenias
- Splenic vein thrombosis
- Rheumatoid arthritis (Felty’s syndrome)
- Systemic lupus erythematosus
- Sarcoidosis
- Wilson’s disease
- Amyloidosis
- Budd-Chiari syndrome
- Gaucher disease
- Niemann-Pick disease
- Splenic cysts, hemangiomas, hamartomas, fibromas
- Metastases, eg, melanoma
- Eosinophilic granuloma (Langerhans cell histiocytosis, histiocytosis X)
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Citation
Zeiger, Roni F.. "Splenomegaly." Diagnosaurus, 4th ed., McGraw-Hill Education, 2015. Emergency Central, emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114508/all/Splenomegaly.
Zeiger RFR. Splenomegaly. Diagnosaurus. McGraw-Hill Education; 2015. https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114508/all/Splenomegaly. Accessed March 30, 2023.
Zeiger, R. F. (2015). Splenomegaly. In Diagnosaurus (4th ed.). McGraw-Hill Education. https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114508/all/Splenomegaly
Zeiger RFR. Splenomegaly [Internet]. In: Diagnosaurus. McGraw-Hill Education; 2015. [cited 2023 March 30]. Available from: https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114508/all/Splenomegaly.
* Article titles in AMA citation format should be in sentence-case
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T1 - Splenomegaly
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BT - Diagnosaurus
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DB - Emergency Central
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