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Osteomalacia

Osteomalacia is a topic covered in the Diagnosaurus.

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Etiology

Vitamin disorders

  • Vitamin D deficiency (malnutrition, insufficient sun exposure, malabsorption, nephrotic syndrome
  • Vitamin D-dependent rickets type I (genetic)
  • Phenytoin, carbamazepine, or barbiturates
Dietary
  • Dietary calcium deficiency
Phosphate deficiency
  • Decreased intestinal absorption
  • Nutritional phosphorus deficiency
  • Malabsorption
  • Phosphate-binding antacid therapy
  • Increased renal loss
  • X-linked hypophosphatemic rickets
  • Oncogenic hypophosphatemic osteomalacia
  • Other disorders: paraproteinemias, glycogen storage diseases, neurofibromatosis, Wilson's disease, Fanconi's syndrome
Inhibitors of mineralization
  • Aluminum
  • Bisphosphonates
Disorders of bone matrix
  • Hypophosphatasia (genetic)
  • Fibrogenesis imperfecta
  • Axial osteomalacia

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Last updated: December 1, 2014

Citation

Zeiger, Roni F.. "Osteomalacia." Diagnosaurus, 4th ed., McGraw-Hill Education, 2014. Emergency Central, emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114316/all/Osteomalacia.
Zeiger RF. Osteomalacia. Diagnosaurus. 4th ed. McGraw-Hill Education; 2014. https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114316/all/Osteomalacia. Accessed April 20, 2019.
Zeiger, R. F. (2014). Osteomalacia. In Diagnosaurus. Available from https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114316/all/Osteomalacia
Zeiger RF. Osteomalacia [Internet]. In: Diagnosaurus. McGraw-Hill Education; 2014. [cited 2019 April 20]. Available from: https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114316/all/Osteomalacia.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Osteomalacia ID - 114316 A1 - Zeiger,Roni F, Y1 - 2014/12/01/ BT - Diagnosaurus UR - https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114316/all/Osteomalacia PB - McGraw-Hill Education ET - 4 DB - Emergency Central DP - Unbound Medicine ER -