Diabetes insipidus
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Etiology
Central (vasopressin deficiency)
- Primary (familial or idiopathic)
- Damage to hypothalamus or pituitary stalk by:
- Metastatic tumor
- Pituitary adenoma
- Anoxic encephalopathy
- Surgical or accidental trauma
- Encephalitis, tuberculosis (TB), syphilis
- Empty sella syndrome
- Radiation
- Sarcoidosis
- Eosinophilic granuloma (Langerhans cell histiocytosis, histiocytosis X)
- Vasopressinase-induced diabetes insipdus (DI) in pregnancy
- Congenital
- Drugs: glucocorticoids, diuretics, demeclocycline, tetracycline, lithium, foscarnet, methicillin
- Acquired: pyelonephritis, amyloidosis, multiple myeloma, hypokalemia, Sjögren's syndrome, sickle cell anemia, hypercalcemia, recovery from acute tubular necrosis (ATN)
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Etiology
Central (vasopressin deficiency)
- Primary (familial or idiopathic)
- Damage to hypothalamus or pituitary stalk by:
- Metastatic tumor
- Pituitary adenoma
- Anoxic encephalopathy
- Surgical or accidental trauma
- Encephalitis, tuberculosis (TB), syphilis
- Empty sella syndrome
- Radiation
- Sarcoidosis
- Eosinophilic granuloma (Langerhans cell histiocytosis, histiocytosis X)
- Vasopressinase-induced diabetes insipdus (DI) in pregnancy
- Congenital
- Drugs: glucocorticoids, diuretics, demeclocycline, tetracycline, lithium, foscarnet, methicillin
- Acquired: pyelonephritis, amyloidosis, multiple myeloma, hypokalemia, Sjögren's syndrome, sickle cell anemia, hypercalcemia, recovery from acute tubular necrosis (ATN)
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