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Diabetes insipidus

Diabetes insipidus is a topic covered in the Diagnosaurus.

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Etiology

Central (vasopressin deficiency)

  • Primary (familial or idiopathic)
  • Damage to hypothalamus or pituitary stalk by:
    • Metastatic tumor
    • Pituitary adenoma
    • Anoxic encephalopathy
    • Surgical or accidental trauma
    • Encephalitis, tuberculosis (TB), syphilis
    • Empty sella syndrome
    • Radiation
    • Sarcoidosis
    • Eosinophilic granuloma (Langerhans cell histiocytosis, histiocytosis X)
  • Vasopressinase-induced diabetes insipdus (DI) in pregnancy
Nephrogenic (vasopressin resistant)
  • Congenital
  • Drugs: glucocorticoids, diuretics, demeclocycline, tetracycline, lithium, foscarnet, methicillin
  • Acquired: pyelonephritis, amyloidosis, multiple myeloma, hypokalemia, Sjögren's syndrome, sickle cell anemia, hypercalcemia, recovery from acute tubular necrosis (ATN)

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Last updated: December 1, 2014

Citation

Zeiger, Roni F.. "Diabetes Insipidus." Diagnosaurus, 4th ed., McGraw-Hill Education, 2014. Emergency Central, emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114300/all/Diabetes_insipidus.
Zeiger RF. Diabetes insipidus. Diagnosaurus. 4th ed. McGraw-Hill Education; 2014. https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114300/all/Diabetes_insipidus. Accessed April 19, 2019.
Zeiger, R. F. (2014). Diabetes insipidus. In Diagnosaurus. Available from https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114300/all/Diabetes_insipidus
Zeiger RF. Diabetes Insipidus [Internet]. In: Diagnosaurus. McGraw-Hill Education; 2014. [cited 2019 April 19]. Available from: https://emergency.unboundmedicine.com/emergency/view/Diagnosaurus/114300/all/Diabetes_insipidus.
* Article titles in AMA citation format should be in sentence-case
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