Arthritis, general DDx

DDx

  • Osteoarthritis (degenerative joint disease) or inflammatory osteoarthritis
  • Connective tissue disease, eg, rheumatoid arthritis, systemic lupus erythematosus, scleroderma, Sjögren’s syndrome, adult Still’s disease
  • Seronegative spondyloarthropathy, eg, reactive arthritis (Reiter’s syndrome), psoriatic arthritis, ankylosing spondylitis, inflammatory bowel disease
  • Infection, eg, Staphylococcus aureus septic arthritis, gonococcal arthritis, endocarditis, hepatitis B or hepatitis C, parvovirus B19, Lyme disease, rubella or post-rubella vaccination
  • Crystal-induced, eg, gout, pseudogout
  • Trauma
  • Other joint disease, eg, Charcot (neuropathic) joint, sarcoidosis, tumor, paraneoplastic syndrome (eg, hypertrophic pulmonary osteoarthropathy, leukemia), avascular necrosis, amyloidosis, coagulopathy, sickle cell disease, Henoch-Schönlein purpura, relapsing polychondritis, Behçet’s syndrome, Whipple’s disease, palindromic rheumatism, ochronosis (alkaptonuria)
  • Other non-joint disease, eg, tendonitis, bursitis, polymyalgia rheumatica, reflex sympathetic dystrophy

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Last updated: December 1, 2014