General

Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.

Pronunciation:
don kwi


Trade Name(s)

  • Angelica sinensis
  • Chinese Angelica
  • Dang Gui
  • Danggui
  • Don Quai
  • Ligustilides
  • Phytoestrogen
  • Radix angelicae gigantis
  • Tang Kuei
  • Tan Kue Bai Zhi

Ther. Class.
none assigned

Common Uses

  • Premenstrual syndrome
  • Various uses as a blood purifier
  • Topically in combination with other ingredients for premature ejaculation

Action

  • May have vasodilating and antispasmodic properties.
  • Binds to estrogen receptors.

Therapeutic Effect(s):

Improved ejaculatory latency.

Pharmacokinetics

Absorption: Unknown.

Distribution: Unknown.

Metabolism and Excretion: Unknown.

Half-life: Unknown.

TIME/ACTION PROFILE

ROUTEONSETPEAKDURATION
POunknownunknownunknown

Contraindication/Precautions

Contraindicated in:

  • Allergy to carrot, celery, mugwort, or other members of the Apiaceae family;
  • OB: Pregnancy and lactation.

Use Cautiously in:

  • Hormone sensitive cancers and conditions (may exacerbate effects or stimulate growth of cancer cells);
  • Protein S deficiency (↑ risk for thrombosis);
  • Surgery (discontinue 2 wk prior to procedure).

Adverse Reactions/Side Effects

Derm: photosensitivity

GI: diarrhea

Misc: Some constituents are carcinogenic and mutagenic

* CAPITALS indicate life-threatening.
Underline indicate most frequent.

Interactions

Natural Drug Interaction

Natural-Natural:

Herbs with antiplatelet or anticoagulant properties may increase bleeding risk when combined with dong quai including: angelica, clove, danshen, garlic, ginger, ginkgo, Panax ginseng , and willow .

Route/Dosage

PO: (Adults) Bulk herb– 3–4.5 g per day in divided doses with meals; Extract– 1 mL (20–40 drops) three times daily.

Availability

Bulk herb: OTC

Extract: OTC

Assessment

  • Assess pain and menstrual patterns prior to and following menstrual cycle to determine effectiveness of this herbal supplement.
  • Assess for pregnancy prior to recommending use of the herbal supplement and warn women not to take this herb if pregnancy is planned or suspected.
  • Assess for history of hormone sensitive cancers or conditions and warn against use.
  • Assess medication profile including prescription and over-the-counter use of products such as aspirin- and ibuprofen-based products to treat menstrual pain.

Potential Diagnoses

Implementation

  • PO: Take with meals.

Patient/Family Teaching

  • Warn patients not to take this medication if pregnant or breast feeding.
  • Inform patients to avoid use of aspirin or other NSAIDs concurrently because of the risk of bleeding.
  • Notify patients that there are no studies supporting the use of this herbal supplement for treatment of menopausal symptoms.
  • Tell patients to consult their health care professional if taking prescription medications before taking dong quai.
  • Discontinue the herbal supplement if diarrhea or excessive bleeding occurs and contact a health care provider if symptoms do not resolve.
  • Instruct patients that photosensitivity may occur and to wear sunscreen and protective clothing if sun exposure is anticipated.

Evaluation/Desired Outcomes

Reduction in menstrual pain and cramping and regular periods with normal flow.

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Citation

* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - dong quai ID - 51239 A1 - Quiring,Courtney, AU - Sanoski,Cynthia A, AU - Vallerand,April Hazard, BT - Davis's Drug Guide UR - https://emergency.unboundmedicine.com/emergency/view/Davis-Drug-Guide/51239/all/dong_quai PB - F.A. Davis Company ET - 16 DB - Emergency Central DP - Unbound Medicine ER -