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thymus extract


Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.


Trade Name(s)

  • thymomodulin
  • thymostimulin
  • thymus polypeptides

Ther. Class.
immune stimulants
allergy, cold and cough remedies

Common Uses

  • Respiratory infections.
  • Allergic rhinitis.
  • Asthma.
  • Food allergies.


Thymus extract is derived from bovine thymus glands. It induces T-lymphocyte maturation, stimulates T-cell proliferation, enhances mature T-cell function and has indirect effects on macrophages and B-cell functions. It also reduces airway hyperresponsiveness to methacholine in atopic asthma patients.

Therapeutic Effect(s):

  • Improved immune function.
  • Reduced acute asthma attacks.


Absorption: Unknown

Distribution: Unknown

Metabolism and Excretion: Unknown

Half-life: Unknown




Contraindicated in:

  • Hypersensitivity.
  • Immunocompromised patients should only use products that are certified pathogen-free to reduce the risk of infection from diseased animal parts.

Use Cautiously in:

Pregnancy and lactation.

Adverse Reactions/Side Effects

Misc: Potential risk of contamination from diseased animal parts.

* CAPITALS indicate life-threatening.
Underline indicate most frequent.


Natural Drug Interaction

Avoid use with immunosuppressants unless products are certified pathogen-free.




PO: (Adults) 750 mg/day of crude thymus polypeptide fraction or 120 mg/day of pure thymus polypeptides (thymomodulin).




  • Assess symptoms of cold or allergies related to the purpose thymus extract is being taken.

Potential Diagnoses

  • Risk for infection (Indications)


  • PO: Administer as recommended.

Patient/Family Teaching

  • Discuss with patient purpose for taking thymus extract.
  • Advise patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care professional before taking other medications.
  • Advise female patient to notify health care professional if pregnancy is planned or suspected or if breastfeeding.

Evaluation/Desired Outcomes

Improvement in symptoms of cold or allergic rhinitis.

thymus extract is a sample topic from the Davis's Drug Guide.

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Quiring, Courtney, et al. "Thymus Extract." Davis's Drug Guide, 16th ed., F.A. Davis Company, 2019. Emergency Central, emergency.unboundmedicine.com/emergency/view/Davis-Drug-Guide/110116/all/thymus_extract.
Quiring C, Sanoski CA, Vallerand AH. Thymus extract. Davis's Drug Guide. 16th ed. F.A. Davis Company; 2019. https://emergency.unboundmedicine.com/emergency/view/Davis-Drug-Guide/110116/all/thymus_extract. Accessed April 24, 2019.
Quiring, C., Sanoski, C. A., & Vallerand, A. H. (2019). Thymus extract. In Davis's Drug Guide. Available from https://emergency.unboundmedicine.com/emergency/view/Davis-Drug-Guide/110116/all/thymus_extract
Quiring C, Sanoski CA, Vallerand AH. Thymus Extract [Internet]. In: Davis's Drug Guide. F.A. Davis Company; 2019. [cited 2019 April 24]. Available from: https://emergency.unboundmedicine.com/emergency/view/Davis-Drug-Guide/110116/all/thymus_extract.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - thymus extract ID - 110116 A1 - Quiring,Courtney, AU - Sanoski,Cynthia A, AU - Vallerand,April Hazard, BT - Davis's Drug Guide UR - https://emergency.unboundmedicine.com/emergency/view/Davis-Drug-Guide/110116/all/thymus_extract PB - F.A. Davis Company ET - 16 DB - Emergency Central DP - Unbound Medicine ER -