Eczema/atopic Dermatitis
Basics
Description
Description
- Atopic dermatitis is the most common cause of eczema and the terms are often used synonymously:
- Associated with allergic diseases such as asthma and allergic rhinitis
- Eczema literally means “out boil” and refers to spongiosis, the process where microvesicles form and rupture, leaving erythema, edema, crusting, and oozing
- Pruritus is highly characteristic:
- Patient scratching causes skin breakdown with oozing and crusting
- Chronic response is epidermal hyperplasia and hyperkeratosis
- 90% of patients colonize with Staphylococcus aureus, and are prone to episodes of superinfection
Risk Factors
GeneticsRisk Factors
- Family history of atopy (asthma, allergic rhinitis)
- Mutation of the filaggrin protein (part of the epidermal barrier) is strongly associated
Etiology
Etiology
Atopic dermatitis is caused by a deficit in epidermal integrity that allows foreign substances to enter and trigger immune responses
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Citation
Schaider, Jeffrey J., et al., editors. "Eczema/atopic Dermatitis." 5-Minute Emergency Consult, 6th ed., Lippincott Williams & Wilkins, 2020. Emergency Central, emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307746/all/Eczema_atopic_Dermatitis.
Eczema/atopic Dermatitis. In: Schaider JJJ, Barkin RMR, Hayden SRS, et al, eds. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2020. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307746/all/Eczema_atopic_Dermatitis. Accessed October 11, 2024.
Eczema/atopic Dermatitis. (2020). In Schaider, J. J., Barkin, R. M., Hayden, S. R., Wolfe, R. E., Barkin, A. Z., Shayne, P., & Rosen, P. (Eds.), 5-Minute Emergency Consult (6th ed.). Lippincott Williams & Wilkins. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307746/all/Eczema_atopic_Dermatitis
Eczema/atopic Dermatitis [Internet]. In: Schaider JJJ, Barkin RMR, Hayden SRS, Wolfe RER, Barkin AZA, Shayne PP, Rosen PP, editors. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2020. [cited 2024 October 11]. Available from: https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307746/all/Eczema_atopic_Dermatitis.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Eczema/atopic Dermatitis
ID - 307746
ED - Barkin,Adam Z,
ED - Shayne,Philip,
ED - Rosen,Peter,
ED - Schaider,Jeffrey J,
ED - Barkin,Roger M,
ED - Hayden,Stephen R,
ED - Wolfe,Richard E,
BT - 5-Minute Emergency Consult
UR - https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307746/all/Eczema_atopic_Dermatitis
PB - Lippincott Williams & Wilkins
ET - 6
DB - Emergency Central
DP - Unbound Medicine
ER -