Eczema/atopic Dermatitis

Eczema/atopic Dermatitis is a topic covered in the 5-Minute Emergency Consult.

To view the entire topic, please or .

Emergency Central is a collection of disease, drug, and test information including 5-Minute Emergency Medicine Consult, Davis’s Drug, McGraw-Hill Medical’s Diagnosaurus®, Pocket Guide to Diagnostic Tests, and MEDLINE Journals created for emergency medicine professionals. Explore these free sample topics:

-- The first section of this topic is shown below --

Basics

Description

  • Atopic dermatitis is the most common cause of eczema and the terms are often used synonymously:
    • Associated with allergic diseases such as asthma and allergic rhinitis
  • Eczema literally means “out boil” and refers to spongiosis, the process where microvesicles form and rupture, leaving erythema, edema, crusting, and oozing
  • Pruritus is highly characteristic:
    • Patient scratching causes skin breakdown with oozing and crusting
    • Chronic response is epidermal hyperplasia and hyperkeratosis
  • 90% of patients colonize with Staphylococcus aureus, and are prone to episodes of superinfection

Risk Factors

Genetics
  • Family history of atopy (asthma, allergic rhinitis)
  • Mutation of the filaggrin protein (part of the epidermal barrier) is strongly associated

Etiology

Atopic dermatitis is caused by a deficit in epidermal integrity that allows foreign substances to enter and trigger immune responses

-- To view the remaining sections of this topic, please or --

Basics

Description

  • Atopic dermatitis is the most common cause of eczema and the terms are often used synonymously:
    • Associated with allergic diseases such as asthma and allergic rhinitis
  • Eczema literally means “out boil” and refers to spongiosis, the process where microvesicles form and rupture, leaving erythema, edema, crusting, and oozing
  • Pruritus is highly characteristic:
    • Patient scratching causes skin breakdown with oozing and crusting
    • Chronic response is epidermal hyperplasia and hyperkeratosis
  • 90% of patients colonize with Staphylococcus aureus, and are prone to episodes of superinfection

Risk Factors

Genetics
  • Family history of atopy (asthma, allergic rhinitis)
  • Mutation of the filaggrin protein (part of the epidermal barrier) is strongly associated

Etiology

Atopic dermatitis is caused by a deficit in epidermal integrity that allows foreign substances to enter and trigger immune responses

There's more to see -- the rest of this entry is available only to subscribers.