Emergency Central is a collection of disease, drug, and test information including 5-Minute Emergency Medicine Consult, Davis’s Drug, McGraw-Hill Medical’s Diagnosaurus®, Pocket Guide to Diagnostic Tests, and MEDLINE Journals created for emergency medicine professionals. Explore these free sample topics:
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- Atopic dermatitis is the most common cause of eczema and the terms are often used synonymously.
- Associated with allergic diseases such as asthma and allergic rhinitis
- Eczema literally means “out boil” and refers to spongiosis, the process where microvesicles form and rupture, leaving erythema, edema, crusting, and oozing
- Pruritus is highly characteristic
- Patient rub and scratch skin breakdown with oozing and crusting
- Chronically this causes epidermal hyperplasia and hyperkeratosis
- 90% of patients colonize with Staphylococcus aureus, and are prone to episodes of superinfection
- Family history of atopy (asthma, allergic rhinitis) typical
- Mutation of the filaggrin protein, part of the epidermal barrier, is strongly associated
Atopic dermatitis is caused by a deficit in epidermal integrity that allows foreign substances to enter and trigger immune responses.