Parkinson Disease is a topic covered in the 5-Minute Emergency Consult.

To view the entire topic, please or purchase a subscription.

Emergency Central is a collection of disease, drug, and test information including 5-Minute Emergency Medicine Consult, Davis’s Drug, McGraw-Hill Medical’s Diagnosaurus®, Pocket Guide to Diagnostic Tests, and MEDLINE Journals created for emergency medicine professionals. Explore these free sample topics:

Emergency Central

-- The first section of this topic is shown below --

Basics

Description

  • Gradual progressive neurologic disorder of middle or late life
  • Degeneration of dopaminergic neurons in the substantia nigra
  • Development of Lewy bodies in the residual dopaminergic neurons
  • Accelerated cortical atrophy
  • Can begin unilaterally, but generalizes to symmetric
  • Affects 1% of people >60 yr; 4% >80 yr
  • May have symptoms 20 yr prior to diagnosis
    • Nonspecific:
      • Fatigue
      • Constipation
      • Hyposomia

Etiology

  • Sporadic or idiopathic
  • Disorders presenting with parkinsonism:
    • Drug induced:
      • Parkinsonism-hyperpyrexia syndrome (dopaminergic drug withdrawal)
      • Amphotericin B
      • Chemotherapeutic drugs
      • Neuroleptic treatment induced
    • Toxins:
      • Carbon monoxide
      • Methanol
      • Cyanide
      • Organophosphate poisoning
      • 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Brain lesions:
      • Basal ganglia stroke
      • Midbrain lesions
      • Hydrocephalus
    • Infections:
      • Mycoplasma
      • Viral encephalitis
    • Other:
      • Central pontine myelinosis
      • Encephalitis lethargica (autoantibodies against basal ganglia antigens)

-- To view the remaining sections of this topic, please or purchase a subscription --

Citation

* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Parkinson Disease ID - 307675 Y1 - 2016 PB - 5-Minute Emergency Consult UR - https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307675/all/Parkinson_Disease ER -