Vomiting, Cyclic
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Basics
Description
- An idiopathic disorder characterized by recurrent, discrete episodes of disabling nausea and vomiting, abdominal pain lasting hours to days, separated by symptom-free intervals
- More common in pediatric population but increase in recognition of among adults
- Adult population – average age of diagnosis is 31:
- Average age of onset is 21
- Pediatric population – average age of diagnosis is 9
- General characteristics:
- Phase 1: Interepisodic phase:
- Symptom free
- Phase 2: Prodrome:
- Varying intensity of nausea, diaphoresis, abdominal pain
- Phase 3: Emetic phase:
- Intense nausea, vomiting, abdominal pain and lethargy up to 7 d
- Phase 4: Recovery phase:
- Improvement of nausea and tolerance of PO intake
- Phase 1: Interepisodic phase:
Epidemiology
Incidence and Prevalence Estimates- True incidence and prevalence in adult general population unknown due to limited data and research, but there is an increase in recognition of syndrome
- In pediatric population, cyclic vomiting syndrome affects 0.04–2% of population with estimated new cases 3/100,000 annually
Etiology
- Etiology unknown
- Pathophysiology is also unknown and is under research:
- Limited research suggests multifactorial factors such as autonomic, central, and environmental to be involved
-- To view the remaining sections of this topic, please log in or purchase a subscription --
Basics
Description
- An idiopathic disorder characterized by recurrent, discrete episodes of disabling nausea and vomiting, abdominal pain lasting hours to days, separated by symptom-free intervals
- More common in pediatric population but increase in recognition of among adults
- Adult population – average age of diagnosis is 31:
- Average age of onset is 21
- Pediatric population – average age of diagnosis is 9
- General characteristics:
- Phase 1: Interepisodic phase:
- Symptom free
- Phase 2: Prodrome:
- Varying intensity of nausea, diaphoresis, abdominal pain
- Phase 3: Emetic phase:
- Intense nausea, vomiting, abdominal pain and lethargy up to 7 d
- Phase 4: Recovery phase:
- Improvement of nausea and tolerance of PO intake
- Phase 1: Interepisodic phase:
Epidemiology
Incidence and Prevalence Estimates- True incidence and prevalence in adult general population unknown due to limited data and research, but there is an increase in recognition of syndrome
- In pediatric population, cyclic vomiting syndrome affects 0.04–2% of population with estimated new cases 3/100,000 annually
Etiology
- Etiology unknown
- Pathophysiology is also unknown and is under research:
- Limited research suggests multifactorial factors such as autonomic, central, and environmental to be involved
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