Vomiting, Cyclic
Basics
Description
Description
- An idiopathic disorder characterized by recurrent, discrete episodes of disabling nausea and vomiting, abdominal pain lasting hours to days, separated by symptom-free intervals
- More common in pediatric population but increase in recognition of among adults
- Adult population – average age of diagnosis is 31:
- Average age of onset is 21
- Pediatric population – average age of diagnosis is 9
- General characteristics:
- Phase 1: Interepisodic phase:
- Symptom free
- Phase 2: Prodrome:
- Varying intensity of nausea, diaphoresis, abdominal pain
- Phase 3: Emetic phase:
- Intense nausea, vomiting, abdominal pain and lethargy up to 7 d
- Phase 4: Recovery phase:
- Improvement of nausea and tolerance of PO intake
- Phase 1: Interepisodic phase:
Epidemiology
Incidence and Prevalence EstimatesEpidemiology
- True incidence and prevalence in adult general population unknown due to limited data and research, but there is an increase in recognition of syndrome
- In pediatric population, cyclic vomiting syndrome affects 0.04–2% of population with estimated new cases 3/100,000 annually
Etiology
Etiology
- Etiology unknown
- Pathophysiology is also unknown and is under research:
- Limited research suggests multifactorial factors such as autonomic, central, and environmental to be involved
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Citation
Schaider, Jeffrey J., et al., editors. "Vomiting, Cyclic." 5-Minute Emergency Consult, 6th ed., Lippincott Williams & Wilkins, 2020. Emergency Central, emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307673/all/Vomiting__Cyclic.
Vomiting, Cyclic. In: Schaider JJJ, Barkin RMR, Hayden SRS, et al, eds. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2020. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307673/all/Vomiting__Cyclic. Accessed October 15, 2024.
Vomiting, Cyclic. (2020). In Schaider, J. J., Barkin, R. M., Hayden, S. R., Wolfe, R. E., Barkin, A. Z., Shayne, P., & Rosen, P. (Eds.), 5-Minute Emergency Consult (6th ed.). Lippincott Williams & Wilkins. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307673/all/Vomiting__Cyclic
Vomiting, Cyclic [Internet]. In: Schaider JJJ, Barkin RMR, Hayden SRS, Wolfe RER, Barkin AZA, Shayne PP, Rosen PP, editors. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2020. [cited 2024 October 15]. Available from: https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307673/all/Vomiting__Cyclic.
* Article titles in AMA citation format should be in sentence-case
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T1 - Vomiting, Cyclic
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ED - Rosen,Peter,
ED - Schaider,Jeffrey J,
ED - Barkin,Roger M,
ED - Hayden,Stephen R,
ED - Wolfe,Richard E,
BT - 5-Minute Emergency Consult
UR - https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307673/all/Vomiting__Cyclic
PB - Lippincott Williams & Wilkins
ET - 6
DB - Emergency Central
DP - Unbound Medicine
ER -