Legg–calvé–perthes Disease

Legg–calvé–perthes Disease is a topic covered in the 5-Minute Emergency Consult.

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Peripheral Vascular Disease

Abdominal pain, right lower quadrant

dilTIAZem

Arterial blood gases

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Basics

Description

Idiopathic avascular necrosis of the femoral head in children
Genetics:
- Increased frequency with factor V Leiden and anticardiolipin antibodies

Pediatric Considerations
Exclusively a pediatric disease

Etiology

Successive vascular occlusions causing characteristic findings
Growing evidence implicating hypercoagulable states
May be multifactorial
Risk factors include tobacco smoke, wood smoke, low birth weight, birth length <50 cm
Progression through 4 stages of disease:
- Initial stage: Dense femoral head causing intermittent synovitis
- Fragmentation: Femoral head becomes soft and deforms causing loss of motion
- Healing: New bone grows into femoral head
- Residual: Healed femoral head with some deformity
More common in boys: Male > female, 4:1
More common among Caucasians
Most commonly occurs between ages of 3 and 7:
- Range 18 mo–18 yr
Bilateral in 10–15% of cases
Associated with short stature, deprived populations, delayed & disproportionate growth

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Citation

"Legg–calvé–perthes Disease." 5-Minute Emergency Consult, 5th ed., Lippincott Williams & Wilkins, 2016. Emergency Central, emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307669/all/Legg–calvé–perthes_Disease.

Legg–calvé–perthes Disease. 5-Minute Emergency Consult. 5th ed. Lippincott Williams & Wilkins; 2016. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307669/all/Legg–calvé–perthes_Disease. Accessed December 19, 2018.

Legg–calvé–perthes Disease. (2016). In 5-Minute Emergency Consult. Available from https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307669/all/Legg–calvé–perthes_Disease

Legg–calvé–perthes Disease [Internet]. In: 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2016. [cited 2018 December 19]. Available from: https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307669/all/Legg–calvé–perthes_Disease

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TY - ELEC T1 - Legg–calvé–perthes Disease ID - 307669 Y1 - 2016 PB - 5-Minute Emergency Consult UR - https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307669/all/Legg–calvé–perthes_Disease ER -