Emergency Central is a collection of disease, drug, and test information including 5-Minute Emergency Medicine Consult, Davis’s Drug, McGraw-Hill Medical’s Diagnosaurus®, Pocket Guide to Diagnostic Tests, and MEDLINE Journals created for emergency medicine professionals. Explore these free sample topics:
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- CNS depressant effect of isopropanol is 2 to 3 times as potent as that of ethanol.
- Many products that contain isopropanol also contain methanol, ethylene glycol, and ethanol.
- Rapidly absorbed following oral ingestion
- Ketogenic, but does not cause significant acidosis
- Metabolized by alcohol dehydrogenase to acetone (a CNS depressant):
- Concomitant ethanol ingestion doubles half-life of isopropanol but not that of acetone.
- Acetone eliminated by lung and kidney
- Isopropanol: 3–16 hr
- Acetone: 7.5–26 hr
- Isopropanol (isopropyl alcohol): Clear, colorless, volatile liquid with faint odor of acetone and bitter taste
- Available as 70% rubbing alcohol solution:
- May contain blue dye that was added to inhibit its abuse (“blue heaven”)
- Found in:
- Various toiletries
- Window-cleaning solutions
- Paint remover
- Jewelry cleaners
- Hand sanitizers
- Typical adult patient: Chronic alcoholic who has been on drinking binge and recently depleted his or her ethanol supply
- Dermal and rectal administration can cause systemic toxicity.