Depression
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Basics
Description
Major depression:- Depressed mood and associated signs and symptoms lasting more than 2 wk
- Significant morbidity and mortality, including risk of suicide
- Often coexists with other medical illness
Etiology
- Biologic illness associated with derangements in several neurotransmitter systems including serotonin, norepinephrine, and dopamine
- Contributing factors:
- Genetic predisposition
- Psychosocial stress: Depression may follow adverse life event, trauma, loss of important relationship, or life role
- Medical illness
- Higher prevalence in women
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Basics
Description
Major depression:- Depressed mood and associated signs and symptoms lasting more than 2 wk
- Significant morbidity and mortality, including risk of suicide
- Often coexists with other medical illness
Etiology
- Biologic illness associated with derangements in several neurotransmitter systems including serotonin, norepinephrine, and dopamine
- Contributing factors:
- Genetic predisposition
- Psychosocial stress: Depression may follow adverse life event, trauma, loss of important relationship, or life role
- Medical illness
- Higher prevalence in women
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