Barbiturates Poisoning

Barbiturates Poisoning is a topic covered in the 5-Minute Emergency Consult.

To view the entire topic, please or purchase a subscription.

Emergency Central is a collection of disease, drug, and test information including 5-Minute Emergency Medicine Consult, Davis’s Drug, McGraw-Hill Medical’s Diagnosaurus®, Pocket Guide to Diagnostic Tests, and MEDLINE Journals created for emergency medicine professionals. Explore these free sample topics:

Emergency Central

-- The first section of this topic is shown below --

Basics

Description

  • Class of sedative–hypnotic agents
  • Derivatives of barbituric acid
  • Mechanism:
    • Enhances activity of γ-aminobutyric acid (GABA)
    • At high levels, directly opens GABA-A associated chloride channel
    • Leads to inhibition of vascular smooth muscle tone
    • May lead to direct myocardial depression

Etiology

Overdose of barbiturates:
  • Intentional or nonintentional

-- To view the remaining sections of this topic, please or purchase a subscription --