Weakness is a topic covered in the 5-Minute Emergency Consult.

To view the entire topic, please or purchase a subscription.

Emergency Central is a collection of disease, drug, and test information including 5-Minute Emergency Medicine Consult, Davis’s Drug, McGraw-Hill Medical’s Diagnosaurus®, Pocket Guide to Diagnostic Tests, and MEDLINE Journals created for emergency medicine professionals. Explore these free sample topics:

Emergency Central

-- The first section of this topic is shown below --

Basics

Description

  • Defined as a decrease in physical strength or energy
  • Often multifactorial
  • Distinguish neuromuscular disorder vs. non-neuromuscular disorder
  • Categories of neuromuscular disorders:
    • Upper motor neuron (UMN) lesions:
      • Deep tendon reflexes (DTR) increased
      • Plantar reflexes upgoing
      • Increased muscle tone
      • Muscle atrophy absent
    • Lower motor neuron (LMN) lesions:
      • DTRs decreased to absent
      • Plantar reflexes absent or normal
      • Decreased muscle tone
      • Muscle atrophy present
      • Fasciculations
    • Neuromuscular junction (NMJ) lesions:
      • DTRs normal
      • Plantar reflexes normal or absent
      • Decreased muscle tone
  • Categories of non-neuromuscular disorders:
    • Infectious
    • Endocrine
    • Metabolic
    • Cardiac
    • Rheumatologic
    • Toxic
    • Psychiatric

Etiology

  • Neuromuscular disorders:
    • UMN lesions:
      • Multiple sclerosis
      • Amyotrophic lateral sclerosis (mixed)
      • Transverse myelitis
      • Poliomyelitis
    • LMN lesions:
      • Guillain–Barré syndrome
      • Toxic neuropathies
      • Impingement syndromes
      • Diphtheria
      • Porphyria
      • Seafood toxins
    • NMJ lesions/others:
      • Myasthenia gravis
      • Lambert–Eaton syndrome
      • Botulism
      • Periodic paralysis
      • Tick paralysis
  • Non-neuromuscular disorders:
    • Dehydration
    • Anemia
    • Electrolyte imbalances
    • Malignancy
    • Cerebrovascular accident
    • Head or neck trauma
    • Myocardial ischemia
    • Infection/sepsis:
      • UTI
      • Pneumonia
      • Meningitis
      • Mononucleosis
      • HIV
      • Arborviruses
    • Endocrine abnormalities:
      • Hypothyroidism
      • Adrenal crisis
      • Periodic paralyses
    • Rheumatologic disorders:
      • Systemic lupus erythematosus
      • Polymyalgia rheumatica
    • Toxins:
      • Medications
      • Environmental
      • Carbon monoxide poisoning
      • Cocaine
      • Alcohol

-- To view the remaining sections of this topic, please or purchase a subscription --

Citation

* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Weakness ID - 307494 Y1 - 2016 PB - 5-Minute Emergency Consult UR - https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307494/all/Weakness ER -