Aphthous Ulcers
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Basics
Description
Painful ovoid or round ulcerations on the mucous membranes of the mouth, tongue, or genitals:- Commonly referred to as “canker sores”
Etiology
- Unknown
- Etiology likely multifactorial with some correlation with:
- Immunologic dysfunction; alteration of cell-mediated immune system
- Infection
- Food hypersensitivities (i.e., gluten)
- Vitamin deficiency
- Pregnancy
- Menstruation
- Trauma
- Stress
- Ethnicity/genetics
- Immunodeficiency
- Medications: β-blockers, anti-inflammatory
- Epidemiology: Usually occurs in children and young adults (peak age of onset: Between 10 and 19 yr old)
- Most common inflammatory ulcerative condition of the oral cavity (20–40% of general population)
- More common in women
- May be familial
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Basics
Description
Painful ovoid or round ulcerations on the mucous membranes of the mouth, tongue, or genitals:- Commonly referred to as “canker sores”
Etiology
- Unknown
- Etiology likely multifactorial with some correlation with:
- Immunologic dysfunction; alteration of cell-mediated immune system
- Infection
- Food hypersensitivities (i.e., gluten)
- Vitamin deficiency
- Pregnancy
- Menstruation
- Trauma
- Stress
- Ethnicity/genetics
- Immunodeficiency
- Medications: β-blockers, anti-inflammatory
- Epidemiology: Usually occurs in children and young adults (peak age of onset: Between 10 and 19 yr old)
- Most common inflammatory ulcerative condition of the oral cavity (20–40% of general population)
- More common in women
- May be familial
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