Chest Pain
Basics
Description
- Discomfort in the chest caused by various etiologies, including cardiac, pulmonary, gastrointestinal, and musculoskeletal systems
- Chest pain is a common ED complaint, representing 5% of visits
- Second most common ED complaint:
- 6% of these presentations are life-threatening
- Risk of life-threatening causes increases with advancing age
- Annual ED cost for chest pain exceeds $10 billion
- 40% of patients with chest pain revisit ED within a year
- Often the presenting symptom of a high-risk etiology:
- Acute coronary syndrome
- Pulmonary embolism
- Aortic dissection
- Assume life-threatening until proven otherwise
- Categorization may suggest the underlying etiology, but the presentation of chest pain can be extremely variable and vague
Etiology
- Thoracic pain:
- May involve the myocardium, pericardium, aorta, pulmonary artery, mediastinum, and esophagus
- Pain is deep, visceral, and poorly localized
- Characteristics vary from severe and crushing to mild, burning, or indigestion
- Epigastric pain:
- May involve the descending aorta, diaphragmatic muscles, gallbladder, pancreas, duodenum, and stomach
- Pain is generally referred to the xiphoid region and the back
- Pleuritic pain:
- Inflammation or trauma to the ribs, cartilage, muscles, nerves, pleural or pericardial surface
- Pain increased by breathing, laughing, coughing, sneezing
- Tenderness to palpation may be present
- Chest wall pain:
- Arises from inflammation of skin and subcutaneous structures
- Reproduced by palpation, arm movements, neck extension, and vertical pressure on the head
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Citation
Schaider, Jeffrey J., et al., editors. "Chest Pain." 5-Minute Emergency Consult, 7th ed., Wolters Kluwer, 2027. Emergency Central, emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307450/1.0/Chest_Pain_.
Chest Pain. In: Schaider JJJ, Barkin RMR, Hayden SRS, et al, eds. 5-Minute Emergency Consult. Wolters Kluwer; 2027. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307450/1.0/Chest_Pain_. Accessed July 11, 2026.
Chest Pain. (2027). In Schaider, J. J., Barkin, R. M., Hayden, S. R., Wolfe, R. E., Barkin, A. Z., Shayne, P., & Rosen, P. (Eds.), 5-Minute Emergency Consult (7th ed.). Wolters Kluwer. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307450/1.0/Chest_Pain_
Chest Pain [Internet]. In: Schaider JJJ, Barkin RMR, Hayden SRS, et al, eds. 5-Minute Emergency Consult. Wolters Kluwer; 2027. [cited 2026 July 11]. Available from: https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307450/1.0/Chest_Pain_.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Chest Pain
ID - 307450
ED - Barkin,Adam Z,
ED - Shayne,Philip,
ED - Rosen,Peter,
ED - Schaider,Jeffrey J,
ED - Barkin,Roger M,
ED - Hayden,Stephen R,
ED - Wolfe,Richard E,
BT - 5-Minute Emergency Consult
UR - https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307450/1.0/Chest_Pain_
PB - Wolters Kluwer
ET - 7
DB - Emergency Central
DP - Unbound Medicine
ER -

5-Minute Emergency Consult

