Rheumatic Fever

Rheumatic Fever is a topic covered in the 5-Minute Emergency Consult.

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  • Constellation of symptoms and signs (Jones criteria)
  • Follows group A streptococcal infection (GAS) also known as Streptococcus pyogenes; usually pharyngitis
  • Uncommon in US; most cases are in developing nations
  • Remains a major cause of cardiac morbidity and mortality worldwide with over 230,000 deaths per year
  • Most common in 5- to 15-yr-olds


  • GAS infection
  • Inflammatory, autoimmune response following GAS infection

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