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Arthritis, Juvenile Idiopathic

Arthritis, Juvenile Idiopathic is a topic covered in the 5-Minute Emergency Consult.

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Basics

Description

  • Previously called JRA
  • JIA comprises persistent, unexplained arthritis lasting >6 wk, occurring <17 yr of age, and affecting a heterogeneous group of children.
  • Prevalence up to 1 in 1,000 children
  • Girls > boys for most forms
  • Classified into 7 subgroups: Systemic onset, polyarticular RF+, polyarticular RF-, pauciarticular, psoriatic, enthesitis, other or unclassified.
  • Subtypes are based on number, type, and symmetry of joints involved; presence of systemic symptoms; skin involvement; family history; and lab values.
  • Up to 20% of JIA patients remain unclassified or are classified in multiple categories.
  • Natural course of the disease depends on the subtype (pauciarticular with overall best prognosis), but full resolution occurs in <50% of JIA patients.
  • Many will have a fluctuating course and ongoing disease through adulthood.

Etiology

Believed to be an autoimmune disease triggered by an unknown environmental trigger in a genetically susceptible host

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Citation

Rosen, Peter, et al., editors. "Arthritis, Juvenile Idiopathic." 5-Minute Emergency Consult, 5th ed., Lippincott Williams & Wilkins, 2016. Emergency Central, emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307412/6.1/Arthritis_Juvenile_Idiopathic.
Arthritis, Juvenile Idiopathic. In: Rosen P, Shayne P, Barkin AZ, et al, eds. 5-Minute Emergency Consult. 5th ed. Lippincott Williams & Wilkins; 2016. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307412/6.1/Arthritis_Juvenile_Idiopathic. Accessed June 16, 2019.
Arthritis, Juvenile Idiopathic. (2016). In Rosen, P., Shayne, P., Barkin, A. Z., Wolfe, R. E., Hayden, S. R., Barkin, R. M., & Schaider, J. J. (Eds.), 5-Minute Emergency Consult. Available from https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307412/6.1/Arthritis_Juvenile_Idiopathic
Arthritis, Juvenile Idiopathic [Internet]. In: Rosen P, Shayne P, Barkin AZ, Wolfe RE, Hayden SR, Barkin RM, Schaider JJ, editors. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2016. [cited 2019 June 16]. Available from: https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307412/6.1/Arthritis_Juvenile_Idiopathic.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Arthritis, Juvenile Idiopathic ID - 307412 ED - Rosen,Peter, ED - Shayne,Philip, ED - Barkin,Adam Z, ED - Wolfe,Richard E, ED - Hayden,Stephen R, ED - Barkin,Roger M, ED - Schaider,Jeffrey J, BT - 5-Minute Emergency Consult UR - https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307412/6.1/Arthritis_Juvenile_Idiopathic PB - Lippincott Williams & Wilkins ET - 5 DB - Emergency Central DP - Unbound Medicine ER -