Emergency Central is a collection of disease, drug, and test information including 5-Minute Emergency Medicine Consult, Davis’s Drug, McGraw-Hill Medical’s Diagnosaurus®, Pocket Guide to Diagnostic Tests, and MEDLINE Journals created for emergency medicine professionals. Explore these free sample topics:
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- Chronic systemic inflammatory disorder that attacks the joints:
- Nonsuppurative, proliferative synovitis
- Destruction of the articular cartilage
- Ankylosis of the joint
- Involvement of knee is common.
- Baker cysts may be seen in chronic disease.
- Involvement of spine is limited to cervical region:
- May cause atlantoaxial subluxation
- Rarely results in cord compression
Juvenile rheumatoid arthritis (JRA) is a distinct entity (see “Arthritis, Juvenile Idiopathic”).
- Genetic predisposition related to HLA-DR4
- Female-to-male ratio is 3:1.
- Typical age of onset is between 30 and 50.
- Etiology is unknown.
- Possible triggers include infection and autoimmune response.
- Prevalence is about 1% of both US and world population.