Emergency Central is a collection of disease, drug, and test information including 5-Minute Emergency Medicine Consult, Davis’s Drug, McGraw-Hill Medical’s Diagnosaurus®, Pocket Guide to Diagnostic Tests, and MEDLINE Journals created for emergency medicine professionals. Explore these free sample topics:
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- Alcohol withdrawal is the most common withdrawal syndrome encountered in the emergency department
- Neuroexcitation is the hallmark of alcohol withdrawal
- Alcohol withdrawal may be life threatening.
- More severe symptoms and signs are seen in patients with prior episodes of withdrawal, a process called kindling
- Alcoholism is not uncommon among older adults.
- Age-related increase in alcohol sensitivity
- Alcohol-related problems may be misdiagnosed as normal consequences of aging.
- Chronic alcohol use downregulates GABA (inhibitory) receptors, upregulates NMDA (excitatory) receptors.
- Abstinence or reduction in use leads to increased adrenergic activity because of these receptor adaptations
- 4 components to alcohol withdrawal:
- Early withdrawal
- Withdrawal seizures
- Alcoholic hallucinosis
- Delirium tremens (DTs)
- DTs occur in 5% of patients experiencing alcohol withdrawal
- DTs have a 5–15% mortality rate