5-Minute Emergency Consult
Mdma Poisoning
Mdma Poisoning is a topic covered in the 5-Minute Emergency Consult.
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Basics
Description
Description
- MDMA: 3,4-methylenedioxymethamphetamine (“ecstasy” or “Molly” or “XTC”)
- Schedule I drug manufactured illegally
- Used recreationally:
- Rave parties
- Dance clubs
- College campuses
- Onset of effects: 15–30 min after ingestion
- Duration of effects: 2–6 hr
- Pills commonly contain contaminants:
- Caffeine
- Ephedrine
- Dextromethorphan
- Ketamine
- Related methylated amphetamines: 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxy-N-ethylamphetamine (MDEA), 3,4-methylenedioxy-N-butylamphetamine (MDBA), para-methoxyamphetamine (PMA)
- Pathophysiology:
- Amphetamine-like structure stimulates catecholamine release
- Mescaline-like ring structure enhances serotonergic and dopaminergic activity
Etiology
Etiology
Deliberate or accidental ingestion of MDMA
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Basics
Description
Description
- MDMA: 3,4-methylenedioxymethamphetamine (“ecstasy” or “Molly” or “XTC”)
- Schedule I drug manufactured illegally
- Used recreationally:
- Rave parties
- Dance clubs
- College campuses
- Onset of effects: 15–30 min after ingestion
- Duration of effects: 2–6 hr
- Pills commonly contain contaminants:
- Caffeine
- Ephedrine
- Dextromethorphan
- Ketamine
- Related methylated amphetamines: 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxy-N-ethylamphetamine (MDEA), 3,4-methylenedioxy-N-butylamphetamine (MDBA), para-methoxyamphetamine (PMA)
- Pathophysiology:
- Amphetamine-like structure stimulates catecholamine release
- Mescaline-like ring structure enhances serotonergic and dopaminergic activity
Etiology
Etiology
Deliberate or accidental ingestion of MDMA
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Citation
Schaider, Jeffrey J., et al., editors. "Mdma Poisoning." 5-Minute Emergency Consult, 5th ed., Lippincott Williams & Wilkins, 2016. Emergency Central, emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307339/all/Mdma_Poisoning.
Mdma Poisoning. In: Schaider JJJ, Barkin RMR, Hayden SRS, et al, eds. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2016. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307339/all/Mdma_Poisoning. Accessed April 10, 2021.
Mdma Poisoning. (2016). In Schaider, J. J., Barkin, R. M., Hayden, S. R., Wolfe, R. E., Barkin, A. Z., Shayne, P., & Rosen, P. (Eds.), 5-Minute Emergency Consult (5th edition). Lippincott Williams & Wilkins. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307339/all/Mdma_Poisoning
Mdma Poisoning [Internet]. In: Schaider JJJ, Barkin RMR, Hayden SRS, Wolfe RER, Barkin AZA, Shayne PP, Rosen PP, editors. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2016. [cited 2021 April 10]. Available from: https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307339/all/Mdma_Poisoning.
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