Mdma Poisoning

Mdma Poisoning is a topic covered in the 5-Minute Emergency Consult.

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  • MDMA: 3,4-methylenedioxymethamphetamine (“ecstasy”)
  • Schedule I drug manufactured illegally
  • Used recreationally:
    • Rave parties
    • Dance clubs
    • College campuses
  • Onset of effects: 15–30 min after ingestion
  • Duration of effects: 2–6 hr
  • Pills commonly contain contaminants:
    • Caffeine
    • Ephedrine
    • Dextromethorphan
    • Ketamine
    • Related methylated amphetamines: 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxy-N-ethylamphetamine (MDEA), 3,4-methylenedioxy-N-butylamphetamine (MDBA), para-methoxyamphetamine (PMA)
  • Pathophysiology:
    • Amphetamine-like structure stimulates catecholamine release.
    • Mescaline-like ring structure enhances serotonergic and dopaminergic activity.


Deliberate or accidental ingestion of MDMA

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