Bundle Branch Blocks
Basics
Description
- Impaired ventricular conduction through His–Purkinje bundles
- Incomplete bundle branch block:
- Partial delay in conduction down one bundle
- Quasi-random signal (QRS) complex duration of 100–120 ms
- Complete bundle branch block:
- Absence or delay of conduction down one bundle, with normal conduction down the other bundle
- Affected ventricle depolarizes from muscle to muscle in a slower and more disorganized fashion
- QRS complex at 120 ms or longer
- Right bundle branch block (RBBB):
- Delayed depolarization of the right ventricle causing the right ventricle to depolarize via slower, muscle-to-muscle conduction
- Left bundle branch block (LBBB):
- Delayed depolarization of the left ventricle
- Left bundle branches into 2 fascicles:
- Left anterior fascicle: Initial septal activation proceeds inferiorly, anteriorly, and to the right
- Left posterior fascicle: Isolated blockage rare; activation begins in the midseptum and finishes in inferior and posterior walls
- LBBB can be caused by delay of conduction in main left bundle or delay in both fascicles of the left bundle
- Causes early activation of the right side of the septum and the right ventricular myocardium (so explaining loss of “septal Q” on ECG)
- Bifascicular block:
- RBBB with concomitant block of the left anterior or left posterior fascicle
Etiology
- Myocardial infarction
- Cardiomyopathy
- Myocarditis
- Pulmonary embolism
- Cor pulmonale
- Chronic obstructive pulmonary disease
- Obstructive sleep apnea
- Hypertension
- Age-related fibrosis of Purkinje fibers
- Myocardial Ischemia (myocarditis)
- Valvular heart disease
- Congenital/atrial septal defect
- Progressive cardiac conduction disease
- Chagas disease (Central/South American predominance)
- Rheumatic fever
- Infectious endocarditis
- Tuberculosis involving the pericardium or myocardium
- Postoperative/Iatrogenic following cardiac procedures
- Amyloidosis
- Sarcoidosis
- Hemachromatosis
- Systemic lupus erythematosus
- Radiation therapy
- Drugs:
- β-Blockers
- Calcium blockers
- Tricyclic antidepressants
- Type Ia and Ic antiarrhythmics
- Digitalis
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Citation
Schaider, Jeffrey J., et al., editors. "Bundle Branch Blocks." 5-Minute Emergency Consult, 6th ed., Lippincott Williams & Wilkins, 2020. Emergency Central, emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307334/0.1/Bundle_Branch_Blocks_.
Bundle Branch Blocks. In: Schaider JJJ, Barkin RMR, Hayden SRS, et al, eds. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2020. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307334/0.1/Bundle_Branch_Blocks_. Accessed June 12, 2026.
Bundle Branch Blocks. (2020). In Schaider, J. J., Barkin, R. M., Hayden, S. R., Wolfe, R. E., Barkin, A. Z., Shayne, P., & Rosen, P. (Eds.), 5-Minute Emergency Consult (6th ed.). Lippincott Williams & Wilkins. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307334/0.1/Bundle_Branch_Blocks_
Bundle Branch Blocks [Internet]. In: Schaider JJJ, Barkin RMR, Hayden SRS, et al, eds. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2020. [cited 2026 June 12]. Available from: https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307334/0.1/Bundle_Branch_Blocks_.
* Article titles in AMA citation format should be in sentence-case
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T1 - Bundle Branch Blocks
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ED - Barkin,Adam Z,
ED - Shayne,Philip,
ED - Rosen,Peter,
ED - Schaider,Jeffrey J,
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ED - Hayden,Stephen R,
ED - Wolfe,Richard E,
BT - 5-Minute Emergency Consult
UR - https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307334/0.1/Bundle_Branch_Blocks_
PB - Lippincott Williams & Wilkins
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DB - Emergency Central
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5-Minute Emergency Consult

