Asthma, Adult
Asthma, Adult is a topic covered in the 5-Minute Emergency Consult.
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Basics
Description
Description
- Increased expiratory resistance:
- Airway inflammation
- Bronchospasm
- Mucosal edema
- Mucous plugging
- Smooth muscle hypertrophy
- Consequences:
- Air trapping
- Airway remodeling
- Increased dead space
- Hyperinflation
- Status asthmaticus refers to disease that does not respond to therapy within 30–60 min
- Risk factors for life-threatening disease:
- Prior intubations
- Intensive care unit admissions
- Chronic steroid use
- Hospital admission for asthma during the past year
- Inadequate medical management
- Increasing age
- Ethnicity (African Americans)
- Lack of access to medical care
- Multiple comorbidities
Etiology
Etiology
- Inflammatory process of the airways evidenced by episodic and reversible airflow obstruction and hyper-responsiveness with many cells and cellular elements contributing to the disease:
- Neutrophils
- Mast cells
- Eosinophils
- Macrophages
- T lymphocytes
- Epithelial cells
- Cytokines
- Triggers:
- Pollen
- Dust mites
- Molds
- Animal dander
- Other environmental allergens
- Viral upper respiratory infections
- Occupational chemicals
- Tobacco smoke
- Environmental change
- Cold air
- Exercise induced
- Emotional factors
- Menstrual associated
- Drugs:
- Aspirin
- NSAIDs
- β-blockers
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Citation
Rosen, Peter, et al., editors. "Asthma, Adult." 5-Minute Emergency Consult, 5th ed., Lippincott Williams & Wilkins, 2016. Emergency Central, emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307267/all/Asthma__Adult.
Asthma, Adult. In: Rosen P, Shayne P, Barkin AZ, et al, eds. 5-Minute Emergency Consult. 5th ed. Lippincott Williams & Wilkins; 2016. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307267/all/Asthma__Adult. Accessed December 7, 2019.
Asthma, Adult. (2016). In Rosen, P., Shayne, P., Barkin, A. Z., Wolfe, R. E., Hayden, S. R., Barkin, R. M., & Schaider, J. J. (Eds.), 5-Minute Emergency Consult. Available from https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307267/all/Asthma__Adult
Asthma, Adult [Internet]. In: Rosen P, Shayne P, Barkin AZ, Wolfe RE, Hayden SR, Barkin RM, Schaider JJ, editors. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2016. [cited 2019 December 07]. Available from: https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307267/all/Asthma__Adult.
* Article titles in AMA citation format should be in sentence-case
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T1 - Asthma, Adult
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ED - Barkin,Adam Z,
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ED - Barkin,Roger M,
ED - Schaider,Jeffrey J,
BT - 5-Minute Emergency Consult
UR - https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307267/all/Asthma__Adult
PB - Lippincott Williams & Wilkins
ET - 5
DB - Emergency Central
DP - Unbound Medicine
ER -