Pseudotumor Cerebri

Pseudotumor Cerebri is a topic covered in the 5-Minute Emergency Consult.

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Basics

Description

  • Buildup of CSF pressure without mass lesion or clear etiology
  • Also known as idiopathic intracranial hypertension
  • 2 proposed mechanisms:
    • Increased abdominal pressure or intracranial venous stenosis may decrease venous drainage from the head
    • Vitamin A levels above the saturation of the liver can damage cell membranes in the arachnoid granulations
  • Associated with obesity
  • Average age of onset 30 yr
  • Female predominance (7:1)
  • Uncommon, ∼1–5 cases per 100,000

Etiology

Proposed causative agents:
  • Obesity
  • Obstruction of intracranial venous drainage
  • Hypervitaminosis A
  • Steroids/steroid withdrawal
  • Tetracycline antibiotics
  • Oral contraceptive pills
  • Hypertension
  • Recent weight gain
  • Chronic carbon dioxide retention with elevated intracranial pressure

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Citation

* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Pseudotumor Cerebri ID - 307237 Y1 - 2016 PB - 5-Minute Emergency Consult UR - https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307237/all/Pseudotumor_Cerebri ER -