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Phencyclidine Poisoning

Phencyclidine Poisoning is a topic covered in the 5-Minute Emergency Consult.

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  • Phencyclidine (PCP) is a dissociative anesthetic structurally related to ketamine:
    • Causes decreased perception of pain and agitation
  • Half-life of 21–24 hr, but may be longer in overdose
  • Enterohepatic recirculation—recirculated into the stomach


  • Drug of abuse:
    • Frequently encountered as an adulterant of marijuana
  • Street names for PCP include:
    • Angel dust
    • Wicky stick
    • Wicky weed
    • Wacky weed
    • Wet
    • Illy
    • Embalming fluid
    • Sherman

Pediatric Considerations
Exposure in toddlers reported via passive exposure

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Rosen, Peter, et al., editors. "Phencyclidine Poisoning." 5-Minute Emergency Consult, 5th ed., Lippincott Williams & Wilkins, 2016. Emergency Central, emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307206/all/Phencyclidine_Poisoning.
Phencyclidine Poisoning. In: Rosen P, Shayne P, Barkin AZ, et al, eds. 5-Minute Emergency Consult. 5th ed. Lippincott Williams & Wilkins; 2016. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307206/all/Phencyclidine_Poisoning. Accessed April 25, 2019.
Phencyclidine Poisoning. (2016). In Rosen, P., Shayne, P., Barkin, A. Z., Wolfe, R. E., Hayden, S. R., Barkin, R. M., & Schaider, J. J. (Eds.), 5-Minute Emergency Consult. Available from https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307206/all/Phencyclidine_Poisoning
Phencyclidine Poisoning [Internet]. In: Rosen P, Shayne P, Barkin AZ, Wolfe RE, Hayden SR, Barkin RM, Schaider JJ, editors. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2016. [cited 2019 April 25]. Available from: https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307206/all/Phencyclidine_Poisoning.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Phencyclidine Poisoning ID - 307206 ED - Rosen,Peter, ED - Shayne,Philip, ED - Barkin,Adam Z, ED - Wolfe,Richard E, ED - Hayden,Stephen R, ED - Barkin,Roger M, ED - Schaider,Jeffrey J, BT - 5-Minute Emergency Consult UR - https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307206/all/Phencyclidine_Poisoning PB - Lippincott Williams & Wilkins ET - 5 DB - Emergency Central DP - Unbound Medicine ER -