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Ectopic Pregnancy

Ectopic Pregnancy is a topic covered in the 5-Minute Emergency Consult.

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  • Implantation of fertilized ovum outside of uterus:
    • Most commonly fallopian tube (93–97%)
  • Abdominal and peritoneal implantations:
    • Associated with higher morbidity
    • Difficulty in diagnosis
    • Tendency to bleed
  • Occurs in 2–2.6% of pregnancies
  • Accounts for 6% of all maternal deaths (leading cause of 1st-trimester pregnancy-related death)
  • 60% of women with ectopic pregnancy are subsequently able to have a normal pregnancy


  • Risk factors include:
    • Woman >35 yr old
    • African American
    • Previous fallopian tube damage from infections, such as pelvic inflammatory disease (PID)
    • Previous tubal surgery (i.e., tubal ligation)
    • Previous ectopic pregnancy
    • Intrauterine device (IUD) use:
      • 25–50% of pregnancies with IUD are ectopic
    • Diethylstilbestrol (DES) exposure
    • In vitro fertilizations
    • Being a current smoker
  • More than half of women with ectopic pregnancies have no risk factors

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Rosen, Peter, et al., editors. "Ectopic Pregnancy." 5-Minute Emergency Consult, 5th ed., Lippincott Williams & Wilkins, 2016. Emergency Central, emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307195/all/Ectopic_Pregnancy.
Ectopic Pregnancy. In: Rosen P, Shayne P, Barkin AZ, et al, eds. 5-Minute Emergency Consult. 5th ed. Lippincott Williams & Wilkins; 2016. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307195/all/Ectopic_Pregnancy. Accessed April 22, 2019.
Ectopic Pregnancy. (2016). In Rosen, P., Shayne, P., Barkin, A. Z., Wolfe, R. E., Hayden, S. R., Barkin, R. M., & Schaider, J. J. (Eds.), 5-Minute Emergency Consult. Available from https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307195/all/Ectopic_Pregnancy
Ectopic Pregnancy [Internet]. In: Rosen P, Shayne P, Barkin AZ, Wolfe RE, Hayden SR, Barkin RM, Schaider JJ, editors. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2016. [cited 2019 April 22]. Available from: https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307195/all/Ectopic_Pregnancy.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Ectopic Pregnancy ID - 307195 ED - Rosen,Peter, ED - Shayne,Philip, ED - Barkin,Adam Z, ED - Wolfe,Richard E, ED - Hayden,Stephen R, ED - Barkin,Roger M, ED - Schaider,Jeffrey J, BT - 5-Minute Emergency Consult UR - https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307195/all/Ectopic_Pregnancy PB - Lippincott Williams & Wilkins ET - 5 DB - Emergency Central DP - Unbound Medicine ER -