Type your tag names separated by a space and hit enter

    Staphylococcal Scalded Skin Syndrome

    Staphylococcal Scalded Skin Syndrome is a topic covered in the 5-Minute Emergency Consult.

    To view the entire topic, please or purchase a subscription.

    Emergency Central is a collection of disease, drug, and test information including 5-Minute Emergency Medicine Consult, Davis’s Drug, McGraw-Hill Medical’s Diagnosaurus®, Pocket Guide to Diagnostic Tests, and MEDLINE Journals created for emergency medicine professionals. Explore these free sample topics:

    Emergency Central

    -- The first section of this topic is shown below --

    Basics

    Description

    • Results from the actions of a soluble epidermolytic exotoxin produced by Staphylococcus aureus:
      • Produced at a distant site of infection or colonization
      • Disseminates hematogenously
      • Lyses desmosomes of granular cells in the superficial epidermis
      • Results in generalized intradermal exfoliation
    • Typically affects infants and children <6 yr of age:
      • Adults have specific staph antibodies allowing them to localize, metabolize, and excrete the staph toxins.
      • Infants and children are unable to metabolize and excrete toxin efficiently.
      • Immunocompromised adults and those with severe renal dysfunction are also susceptible
    • Presentation determined by age and extent of rash:
      • Classic staphylococcal scalded skin syndrome
      • Pemphigus neonatorum
      • Bullous impetigo
      • Generalized in the newborn: Ritter disease
    • Typically, coagulase-positive phage group II Staphylococcus:
      • Phage groups I and III also implicated

    Etiology

    • Colonization often without overt infection
    • Concurrent infection or break of skin barrier:
      • Nasopharynx
      • Urinary tract
      • Minor skin abrasions
      • Circumcision site
      • Conjunctivitis
      • Umbilicus/omphalitis
      • Impetigo
      • Endocarditis and septicemia
    • Often no focus identified

    -- To view the remaining sections of this topic, please or purchase a subscription --

    Citation

    * When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
    TY - ELEC T1 - Staphylococcal Scalded Skin Syndrome ID - 307173 ED - Barkin,Adam Z, ED - Barkin,Roger M, ED - Hayden,Stephen R, ED - Rosen,Peter, ED - Schaider,Jeffrey J, ED - Shayne,Philip, ED - Wolfe,Richard E, BT - 5-Minute Emergency Consult UR - https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307173/all/Staphylococcal_Scalded_Skin_Syndrome PB - Lippincott Williams & Wilkins ET - 5 DB - Emergency Central DP - Unbound Medicine ER -