Emergency Central is a collection of disease, drug, and test information including 5-Minute Emergency Medicine Consult, Davis’s Drug, McGraw-Hill Medical’s Diagnosaurus®, Pocket Guide to Diagnostic Tests, and MEDLINE Journals created for emergency medicine professionals. Explore these free sample topics:
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- Postnatal hypertrophy and hyperplasia of the circular smooth muscle cell layer causing a thickened pylorus and antrum leading to progressive gastric outlet obstruction
- Neuronal nitric oxide synthase (NOS-1) may be a genetic susceptibility locus.
- Administration of erythromycin in infants during 1st 2 wk of life may increase risk of hypertrophic pyloric stenosis.
- Jaundice due to transient glucuronyl transferase deficiency
- Adult: Caused by peptic ulcer disease
- Most common cause of GI obstruction in infants; incidence 1/150 males, 1/750 females (average: 3/1,000 live births)
- Males affected 5× more commonly than females; firstborn most common
- Familial, 15%:
- Child of affected parent has 7% incidence.
- Recurrence risk in subsequent male children is 10%; 2% in females.