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Pyloric Stenosis

Pyloric Stenosis is a topic covered in the 5-Minute Emergency Consult.

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Basics

Description

Postnatal hypertrophy and hyperplasia of the circular smooth muscle cell layer causing a thickened pylorus and antrum leading to progressive gastric outlet obstruction
Neuronal nitric oxide synthase (NOS-1) may be a genetic susceptibility locus.
Administration of erythromycin in infants during 1st 2 wk of life may increase risk of hypertrophic pyloric stenosis.
Jaundice due to transient glucuronyl transferase deficiency
Adult: Caused by peptic ulcer disease

Etiology

Most common cause of GI obstruction in infants; incidence 1/150 males, 1/750 females (average: 3/1,000 live births)
Males affected 5× more commonly than females; firstborn most common
Familial, 15%:
- Child of affected parent has 7% incidence.
- Recurrence risk in subsequent male children is 10%; 2% in females.

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Citation

Barkin, Adam Z., et al., editors. "Pyloric Stenosis." 5-Minute Emergency Consult, 5th ed., Lippincott Williams & Wilkins, 2016. Emergency Central, emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307156/all/Pyloric_Stenosis.

Pyloric Stenosis. In: Barkin AZ, Barkin RM, Hayden SR, et al, eds. 5-Minute Emergency Consult. 5th ed. Lippincott Williams & Wilkins; 2016. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307156/all/Pyloric_Stenosis. Accessed February 23, 2019.

Pyloric Stenosis. (2016). In Barkin, A. Z., Barkin, R. M., Hayden, S. R., Rosen, P., Schaider, J. J., Shayne, P., & Wolfe, R. E. (Eds.), 5-Minute Emergency Consult. Available from https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307156/all/Pyloric_Stenosis

Pyloric Stenosis [Internet]. In: Barkin AZ, Barkin RM, Hayden SR, Rosen P, Schaider JJ, Shayne P, Wolfe RE, editors. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2016. [cited 2019 February 23]. Available from: https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307156/all/Pyloric_Stenosis

* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case

TY - ELEC T1 - Pyloric Stenosis ID - 307156 ED - Barkin,Adam Z, ED - Barkin,Roger M, ED - Hayden,Stephen R, ED - Rosen,Peter, ED - Schaider,Jeffrey J, ED - Shayne,Philip, ED - Wolfe,Richard E, BT - 5-Minute Emergency Consult UR - https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307156/all/Pyloric_Stenosis PB - Lippincott Williams & Wilkins ET - 5 DB - Emergency Central DP - Unbound Medicine ER -