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Opiate Poisoning

Opiate Poisoning is a topic covered in the 5-Minute Emergency Consult.

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Basics

Description

  • Bind to μ, κ, and δ opiate receptors in the CNS and peripheral nervous system (PNS)
  • Physical and psychological dependence occurs.
  • Peak plasma levels:
    • PO: 1–2 hr
    • Intramuscular: 0.5–1 hr
    • Intravenous or intranasal: Seconds to minutes

Etiology

  • Overuse or abuse of oral prescription analgesics for moderate to severe pain
  • Street preparations of opiate analogs may contain adulterants:
    • Cocaine
    • Clenbuterol
    • Phencyclidine
    • Strychnine
    • Dextromethorphan
    • Quinine
    • Scopolamine

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Citation

* When formatting your citation, note that all book, journal, and database titles should be italicized* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - Opiate Poisoning ID - 307131 ED - Barkin,Adam Z, ED - Barkin,Roger M, ED - Hayden,Stephen R, ED - Rosen,Peter, ED - Schaider,Jeffrey J, ED - Shayne,Philip, ED - Wolfe,Richard E, BT - 5-Minute Emergency Consult UR - https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307131/all/Opiate_Poisoning PB - Lippincott Williams & Wilkins ET - 5 DB - Emergency Central DP - Unbound Medicine ER -