Opiate Poisoning
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Basics
Description
- Bind to μ, κ, and δ opiate receptors in the CNS and peripheral nervous system (PNS)
- Physical and psychological dependence occurs
- Peak plasma levels:
- PO: 1–2 hr
- Intramuscular: 0.5–1 hr
- Intravenous or intranasal: Seconds to minutes
Etiology
- Overuse or abuse of oral prescription analgesics for moderate to severe pain
- Street preparations of opioid analogs may contain adulterants:
- Cocaine
- Clenbuterol
- Phencyclidine
- Strychnine
- Dextromethorphan
- Quinine
- Scopolamine
-- To view the remaining sections of this topic, please log in or purchase a subscription --
Basics
Description
- Bind to μ, κ, and δ opiate receptors in the CNS and peripheral nervous system (PNS)
- Physical and psychological dependence occurs
- Peak plasma levels:
- PO: 1–2 hr
- Intramuscular: 0.5–1 hr
- Intravenous or intranasal: Seconds to minutes
Etiology
- Overuse or abuse of oral prescription analgesics for moderate to severe pain
- Street preparations of opioid analogs may contain adulterants:
- Cocaine
- Clenbuterol
- Phencyclidine
- Strychnine
- Dextromethorphan
- Quinine
- Scopolamine
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