Syphilis
Basics
Description
Description
- Sexually transmitted disease
- In 2016 there were 88,042 new syphilis diagnoses in the U.S.
- 27,814 new cases of primary or secondary syphilis in the U.S. in 2016, 17.6% increase over 2015
- MSM (men who have sex with men) account for over half of primary and secondary cases diagnosed
- Acquired via mucous membranes/disrupted skin
- Divided into 3 stages:
- Primary syphilis:
- Painless chancre or ulcer
- Secondary syphilis:
- Replication and hematogenous spread
- Begins 3–6 wk after primary lesion
- Rash, mucocutaneous lesions, lymphadenopathy
- Late latent secondary phase
- Tertiary or late syphilis:
- Very uncommon
- Cardiovascular, gummatous, and neurologic symptoms
- Primary syphilis:
Etiology
Etiology
Treponema pallidum
Spirochete bacteria
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Citation
Schaider, Jeffrey J., et al., editors. "Syphilis." 5-Minute Emergency Consult, 6th ed., Lippincott Williams & Wilkins, 2020. Emergency Central, emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307120/all/Syphilis.
Syphilis. In: Schaider JJJ, Barkin RMR, Hayden SRS, et al, eds. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2020. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307120/all/Syphilis. Accessed December 12, 2024.
Syphilis. (2020). In Schaider, J. J., Barkin, R. M., Hayden, S. R., Wolfe, R. E., Barkin, A. Z., Shayne, P., & Rosen, P. (Eds.), 5-Minute Emergency Consult (6th ed.). Lippincott Williams & Wilkins. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307120/all/Syphilis
Syphilis [Internet]. In: Schaider JJJ, Barkin RMR, Hayden SRS, Wolfe RER, Barkin AZA, Shayne PP, Rosen PP, editors. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2020. [cited 2024 December 12]. Available from: https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307120/all/Syphilis.
* Article titles in AMA citation format should be in sentence-case
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T1 - Syphilis
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ED - Hayden,Stephen R,
ED - Wolfe,Richard E,
BT - 5-Minute Emergency Consult
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PB - Lippincott Williams & Wilkins
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DB - Emergency Central
DP - Unbound Medicine
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