Syphilis
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Basics
Description
- Sexually transmitted disease
- In 2016 there were 88,042 new syphilis diagnoses in the U.S.
- 27,814 new cases of primary or secondary syphilis in the U.S. in 2016, 17.6% increase over 2015
- MSM (men who have sex with men) account for over half of primary and secondary cases diagnosed
- Acquired via mucous membranes/disrupted skin
- Divided into 3 stages:
- Primary syphilis:
- Painless chancre or ulcer
- Secondary syphilis:
- Replication and hematogenous spread
- Begins 3–6 wk after primary lesion
- Rash, mucocutaneous lesions, lymphadenopathy
- Late latent secondary phase
- Tertiary or late syphilis:
- Very uncommon
- Cardiovascular, gummatous, and neurologic symptoms
- Primary syphilis:
Etiology
Treponema pallidum
Spirochete bacteria
-- To view the remaining sections of this topic, please log in or purchase a subscription --
Basics
Description
- Sexually transmitted disease
- In 2016 there were 88,042 new syphilis diagnoses in the U.S.
- 27,814 new cases of primary or secondary syphilis in the U.S. in 2016, 17.6% increase over 2015
- MSM (men who have sex with men) account for over half of primary and secondary cases diagnosed
- Acquired via mucous membranes/disrupted skin
- Divided into 3 stages:
- Primary syphilis:
- Painless chancre or ulcer
- Secondary syphilis:
- Replication and hematogenous spread
- Begins 3–6 wk after primary lesion
- Rash, mucocutaneous lesions, lymphadenopathy
- Late latent secondary phase
- Tertiary or late syphilis:
- Very uncommon
- Cardiovascular, gummatous, and neurologic symptoms
- Primary syphilis:
Etiology
Treponema pallidum
Spirochete bacteria
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