Respiratory Distress
Basics
Description
Description
Respiratory distress is the physical manifestation of a patient's difficulty with breathing and is a common complaint in the ED
Etiology
Etiology
- Upper airway obstruction:
- Anaphylaxis
 - Epiglottitis
 - Laryngotracheobronchitis (croup)
 - Foreign body
 - Angioedema
 - Abscess/fluid collection:
- Retropharyngeal abscess
 - Ludwig angina
 - Peritonsillar abscess
 
 
 - Cardiovascular:
- Pulmonary edema/CHF
 - Dysrhythmias
 - Myocardial ischemia
 - Pulmonary embolus
 - Pericarditis
 - Cardiac tamponade
 - Cardiomyopathy
 - Valvular disease
 - Air embolism
 
 - Pulmonary:
- Asthma
 - Chronic obstructive pulmonary disease (COPD)/emphysema
 - Pneumonia
 - Malignancy/SVC syndrome
 - Viral infection (influenza, RSV, etc.)
 - Acute respiratory distress syndrome (ARDS)
 - Pleural effusion
 - Hydrothorax/chylothorax
 - Aspiration
 - Bronchiolitis
 - Bioweapons (anthrax, plague, tularemia, hemorrhagic viruses)
 
 - Trauma:
- Pneumothorax
 - Tension pneumothorax
 - Hemothorax
 - Rib contusion/fractures
 - Pulmonary contusion
 - High cervical spinal injury
 - Fat embolism with long-bone fractures
 
 - Neuromuscular:
- Guillain–Barré syndrome
 - Myasthenia gravis
 
 - Metabolic/systemic/toxic:
- Anemia
 - Acidosis
 - Hyperthyroidism
 - Sepsis
 - Septic emboli (IV drug use or indwelling lines)
 - Overdose (opiates, sedatives, ethanol, salicylate)
 - Sympathomimetic (cocaine, amphetamine, pheochromocytoma)
 - Obesity (deconditioning, restrictive disease)
 - Inhalation injury (smoke, carbon monoxide)
 
 - Psychogenic:
- Anxiety disorder
 - Hyperventilation syndrome
 
 
Pediatric Considerations
- Respiratory failure is a common cause of cardiac arrest in pediatric patients
 - Bronchiolitis:
- <2 yr old
 - Respiratory distress, fine rales, congestion
 - Nasal suction and high-flow O2
 
 - Asthma:
- ≥2 yr old
 - Respiratory distress, wheezing
 - Albuterol/ipratropium nebulizers, steroids, O2
 
 - Croup syndromes include:
- 6 mo–6 yr old
 - Respiratory distress, barking cough, stridor
 - Systemic steroids
 - Racemic epinephrine if stridorous at rest
 
 - Foreign body:
- Young children, often <3 yr old
 - Possible respiratory distress, stridor
 - Upright and lateral decubitus CXRs
 - Utilize specialists to retrieve object given risk of worsening obstruction
 
 - Epiglottitis:
- Highest incidence between 2–4 yr
 - Abrupt onset respiratory distress and stridor
 - Tripod position with poor secretion control, agitation
 - Emergently to OR for airway management; IV antibiotics
 
 
Pregnancy Considerations
- Pulmonary emboli; including thromboembolic, amniotic fluid emboli, and septic emboli from septic abortion or postpartum uterine infection
 - Peripartum dilated cardiomyopathy
 
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Citation
Schaider, Jeffrey J., et al., editors. "Respiratory Distress." 5-Minute Emergency Consult, 6th ed., Lippincott Williams & Wilkins, 2020. Emergency Central, emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307113/all/Respiratory_Distress. 
Respiratory Distress. In: Schaider JJJ, Barkin RMR, Hayden SRS, et al, eds. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2020. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307113/all/Respiratory_Distress. Accessed November 4, 2025.
Respiratory Distress. (2020). In Schaider, J. J., Barkin, R. M., Hayden, S. R., Wolfe, R. E., Barkin, A. Z., Shayne, P., & Rosen, P. (Eds.), 5-Minute Emergency Consult (6th ed.). Lippincott Williams & Wilkins. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307113/all/Respiratory_Distress
Respiratory Distress [Internet]. In: Schaider JJJ, Barkin RMR, Hayden SRS, Wolfe RER, Barkin AZA, Shayne PP, Rosen PP, editors. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2020. [cited 2025 November 04]. Available from: https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307113/all/Respiratory_Distress.
* Article titles in AMA citation format should be in sentence-case
TY  -  ELEC
T1  -  Respiratory Distress
ID  -  307113
ED  -  Barkin,Adam Z,
ED  -  Shayne,Philip,
ED  -  Rosen,Peter,
ED  -  Schaider,Jeffrey J,
ED  -  Barkin,Roger M,
ED  -  Hayden,Stephen R,
ED  -  Wolfe,Richard E,
BT  -  5-Minute Emergency Consult
UR  -  https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307113/all/Respiratory_Distress
PB  -  Lippincott Williams & Wilkins
ET  -  6
DB  -  Emergency Central
DP  -  Unbound Medicine
ER  -  

5-Minute Emergency Consult

