Tenosynovitis
Basics
Description
- Inflammation of the tendon and tendon sheath
- Most common in the hand, wrist, and foot
- Caused by noninfectious (autoimmune, overuse, idiopathic) or infectious processes
- Tendon sheaths consist of synovial sheaths or bursa that cover tendons, as well as osseofibrous tunnels that tendons pass through:
- Visceral and parietal layers of the synovium lubricate and nourish the tendons
- Infection can be introduced into tendon sheath
- Pathophysiology:
- Inflammation and thickening as a result of purulence, autoimmune complexes, crystalline deposits, overuse, or other etiology
- Natural gliding of tendon is disrupted
- Infectious tenosynovitis has 3 stages:
- Distension of the sheath by exudate
- Purulent material invades the sheath
- Necrosis and cell death occurs within the sheath
- Causes of infectious tenosynovitis:
- Skin wound – penetrating injury especially at flexion creases of the finger is most common mechanism that causes flexor tenosynovitis of the hand
- Hematogenous spread
- Nongonococcal infectious tenosynovitis:
- Staphylococcus aureus and Streptococci are most common in penetrating injuries
- Pasteurella multocida is common with cat bites
- Eikenella corrodens is common in human bites
- Pseudomonas is seen in patients with diabetes or marine-associated injuries
- Mycobacterium species may occur in immunocompromised patients
- Fungal tenosynovitis may occur from puncture wounds due to thorns or woody plants
- GC tenosynovitis:
- Caused by Neisseria Gonorrhea
- Most commonly affects teenagers, young adults
- Seen in the ankle, hand, or wrist
- More commonly seen in women
- Vaginal or penile discharge usually absent
- Fever, chills, polyarthralgia are common
- Erythema, tenderness to palpation, and painful range of motion of the involved tendon
- Dermatitis may be present
- Hemorrhagic macules or papules on the distal extremities or trunk
- High-pressure “injection” injury to fingers – may appear minor on the surface but are associated with high incidence of FTS
- Examples:
- Air tools
- Paint sprayers
- Hydraulic equipment
- Causes of noninfectious tenosynovitis:
- De Quervain tenosynovitis:
- Caused by overuse
- Repetitive pinching motion of thumb and fingers
- Inflammatory in nature
- Two thumb tendons can be affected: The abductor pollicis longus (APL) and extensor pollicis brevis (EPB)
- Along the path to the thumb, the APL and EPB traverse side-by-side through a thick fibrous sheath that forms a tunnel at the radial styloid process
- Assembly-line workers
- Carpenters
- Landscaping or weeding
- Rheumatoid tenosynovitis
- Psoriatic tenosynovitis
- De Quervain tenosynovitis:
- Traumatic tenosynovitis is seen after a direct blow to the lower portion of the forearm
Epidemiology
- Incidence approximately 2% in the general population
- Higher among diabetics
- Higher among rheumatoid and psoriatic arthritis
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Citation
Schaider, Jeffrey J., et al., editors. "Tenosynovitis." 5-Minute Emergency Consult, 6th ed., Lippincott Williams & Wilkins, 2020. Emergency Central, emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307108/1.3/Tenosynovitis.
Tenosynovitis. In: Schaider JJJ, Barkin RMR, Hayden SRS, et al, eds. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2020. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307108/1.3/Tenosynovitis. Accessed June 15, 2026.
Tenosynovitis. (2020). In Schaider, J. J., Barkin, R. M., Hayden, S. R., Wolfe, R. E., Barkin, A. Z., Shayne, P., & Rosen, P. (Eds.), 5-Minute Emergency Consult (6th ed.). Lippincott Williams & Wilkins. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307108/1.3/Tenosynovitis
Tenosynovitis [Internet]. In: Schaider JJJ, Barkin RMR, Hayden SRS, et al, eds. 5-Minute Emergency Consult. Lippincott Williams & Wilkins; 2020. [cited 2026 June 15]. Available from: https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307108/1.3/Tenosynovitis.
* Article titles in AMA citation format should be in sentence-case
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5-Minute Emergency Consult

