Emergency Central is a collection of disease, drug, and test information including 5-Minute Emergency Medicine Consult, Davis’s Drug, McGraw-Hill Medical’s Diagnosaurus®, Pocket Guide to Diagnostic Tests, and MEDLINE Journals created for emergency medicine professionals. Explore these free sample topics:
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- Direct or indirect stimulation of adrenergic receptors in sympathetic and central nervous systems
- Often no correlation between dosage and degree of toxicity
- Cocaine may also block sodium channels of cardiac myocytes, leading to “tricyclic” or class 1a–type dysrhythmias.
- Sympathomimetic poisoning in children may present similarly to meningitis or other systemic illness.
- Urinary toxicology screening may be only way to discover sympathomimetic poisoning in children presenting with altered mental status.
- Methylphenidate (Ritalin, Concerta) and other sympathomimetics used for ADHD may cross-react with altered mental status.
- Sympathomimetic toxicity can result from use of any sympathetically active drug, including:
- All amphetamines, methamphetamines, and derivatives (ecstasy, MDMA)
- Synthetic cathinones “Bath Salts”
- Phencyclidine (PCP)
- Lysergic acid diethylamide (LSD)
- Decongestants (rare)
- Drug delivery routes: Inhalation, injection, snorting, or ingestion