5-Minute Emergency Consult
Carbamazepine Poisoning
Basics
Description
- Therapeutic uses of carbamazepine:
- Anticonvulsant
- Treatment of chronic pain
- Migraine prophylaxis
- Mood stabilizer
- Alcohol withdrawal
- Trigeminal neuralgia
- Mechanism:
- Anticholinergic
- Similarities to phenytoin and tricyclic antidepressants (TCAs)
- Stabilizes inactive state of sodium channels
- Decreases synaptic transmission
Etiology
Toxicity may occur from:
- Suicide attempt
- Accidental ingestion
- Supratherapeutic dosing
- Drug–drug interaction
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Citation
Schaider, Jeffrey J., et al., editors. "Carbamazepine Poisoning." 5-Minute Emergency Consult, 7th ed., Wolters Kluwer, 2027. Emergency Central, emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307074/2.0/Carbamazepine_Poisoning.
Carbamazepine Poisoning. In: Schaider JJJ, Barkin RMR, Hayden SRS, et al, eds. 5-Minute Emergency Consult. Wolters Kluwer; 2027. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307074/2.0/Carbamazepine_Poisoning. Accessed July 20, 2026.
Carbamazepine Poisoning. (2027). In Schaider, J. J., Barkin, R. M., Hayden, S. R., Wolfe, R. E., Barkin, A. Z., Shayne, P., & Rosen, P. (Eds.), 5-Minute Emergency Consult (7th ed.). Wolters Kluwer. https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307074/2.0/Carbamazepine_Poisoning
Carbamazepine Poisoning [Internet]. In: Schaider JJJ, Barkin RMR, Hayden SRS, et al, eds. 5-Minute Emergency Consult. Wolters Kluwer; 2027. [cited 2026 July 20]. Available from: https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307074/2.0/Carbamazepine_Poisoning.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Carbamazepine Poisoning
ID - 307074
ED - Barkin,Adam Z,
ED - Shayne,Philip,
ED - Rosen,Peter,
ED - Schaider,Jeffrey J,
ED - Barkin,Roger M,
ED - Hayden,Stephen R,
ED - Wolfe,Richard E,
BT - 5-Minute Emergency Consult
UR - https://emergency.unboundmedicine.com/emergency/view/5-Minute_Emergency_Consult/307074/2.0/Carbamazepine_Poisoning
PB - Wolters Kluwer
ET - 7
DB - Emergency Central
DP - Unbound Medicine
ER -
