Qualitative platelet disorders

Etiology

Acquired disorders

  • Drugs: aspirin, NSAIDs, antibiotics
  • Uremia
  • Myeloproliferative disorder, eg, polycythemia vera, essential thrombocytosis
  • Autoantibody
  • Paraproteins, eg, multiple myeloma
  • Fibrin degradation products
Hereditary disorders
  • von Willebrand’s disease
  • Glanzmann’s thrombasthenia
  • Bernard-Soulier syndrome
  • Storage pool disease, eg, gray platelet syndrome

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