Subcut Remove vial from refrigerator 15 min before injecting to allow to warm to room temperature. Does not require reconstitution or dilution. Solution is clear to slightly opalescent, colorless to slightly yellow; do not administer solutions that are cloudy, discolored, or contain particulate matter. Do not shake vial. Withdraw dose from vial using an 18-gauge needle. Change to 27-gauge, 1/2 inch needle. Inject slowly into abdomen, thigh, or upper arm over 10–60 sec. Inject within 2 hr of preparing dosing syringe; may be refrigerated and used within 8 hr. Discard unused portion of vial.
Instruct patient in correct technique for injection, storage, and place to discard syringes and needles.
Advise patient to notify health care professional immediately if signs and symptoms of hypersensitivity reaction occur.
Advise patient to notify health care professional if pregnancy is planned or suspected or if breastfeeding.
Decrease in frequency, intensity, and duration of symptoms of HAE.
lanadelumab is a sample topic from the Davis's Drug Guide.
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