Topical treatment of interdigital tinea pedis, tinea cruris and tinea corporis.
Inhibits an enzyme necessary for ergosterol synthesis, required for fungal cell membranes.
Antifungal action .
Resolution of dermal fungal infection.
Active against Trichyphyton rubrum and Epidermpophyton floccosum.
Absorption: Small amounts are systemically absorbed.
Protein Binding: >99%
Metabolism and Excretion: Unknown.
TIME/ACTION PROFILE (improvement/resolution of infection)
†Following initiation of treatment.
Use Cautiously in:
OB: Lactation: Safety not established;
Pedi: Safety and effectiveness not established.
Adverse Reactions/Side Effects
Derm: application site reactions
* CAPITALS indicate life-threatening. Underline indicate most frequent.
May inhibit the activity of the CYP2C19 enzymes.
Topical (Adults) Interdigital tinea pedisApply to affected and surrounding areas once daily for two weeks; Tinea cruris and tinea corporisApply to affected and surrounding areas once daily for one week.
Inspect involved areas of skin and mucous membranes before and frequently during therapy. Increased skin irritation may indicate need to discontinue medication.
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