Instruct patient to take prucalopride as directed. Advise patient to read Patient Information before starting therapy and with each Rx refill in case of changes.
Advise patient and family members to discontinue prucalopride and notify health care professional immediately if suicidal ideation and behavior (unusual changes in mood or behavior, persistent worsening of depression, feeling sad or hopeless, thoughts or attempts at self harm, emergence of suicidal thoughts or behavior) occur.
Instruct patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and consult health care professional before taking any new medications.
Rep: Advise females of reproductive potential to notify health care professional if pregnancy is planned or suspected, or if breastfeeding. Inform patient of pregnancy exposure registry that monitors pregnancy outcomes in women exposed to prucalopride during pregnancy. Register patients by contacting MotherToBaby Pregnancy Studies conducted by the Organization of Teratology Information Specialists at 1-877-311-8972 or visiting https://mothertobaby.org/pregnancy-studies/.