Stridor
Basics
Basics
Basics
Description
Description
Description
- High-pitched audible wheezing and vibratory harsh sounds mainly on inspiration
- Impedance of air movement through the upper airway
- It implies a laryngotracheal airway obstruction
- Inspiratory stridor:
- Occurs due to extrathoracic airway obstruction (above the thoracic inlet)
- During inspiration, the pressure inside the airway falls below atmospheric pressure, leading to airway collapse
- The Bernoulli effect contributes to further narrowing and turbulent airflow
- High pitched, loudest over the neck, worsens with crying, improves with neck extension, suggests supraglottic or glottic obstruction
- Expiratory stridor:
- Occurs due to intrathoracic airway obstruction (below the thoracic inlet, typically in the trachea or bronchi)
- During expiration, intrathoracic pressure rises, causing dynamic airway collapse if the structural integrity is weak
- Low pitched, best heard over the chest, worsens with forced expiration, improves prone, suggests intrathoracic airway collapse
- Biphasic stridor:
- Indicates a fixed, central airway obstruction, usually involving the subglottic area or upper trachea
- Both inspiratory and expiratory airflow is disrupted due to a rigid narrowing of the airway lumen
- Low pitched, best heard over the chest, worsens with forced expiration, improves prone, suggests intrathoracic airway collapse
- Stridor is significantly more common in pediatric populations
- Viral croup causes 90% of all cases of stridor in children:
- Strong seasonal pattern, peaking in late fall and early winter
Etiology
Etiology
Etiology
Pediatric
Pediatric
Pediatric
- Congenital causes:
- Laryngomalacia (most common congenital cause of inspiratory stridor)
- Laryngeal webs/rings
- Vascular anomalies (eg, vascular rings, pulmonary artery sling)
- Congenital subglottic stenosis
- Laryngeal cysts
- Laryngotracheoesophageal clefts
- Congenital vocal cord dysfunction
- Unilateral or bilateral vocal cord paralysis
- Neural abnormalities (eg, meningomyelocele, Arnold–Chiari malformation)
- Congenital myopathies affecting vocal cord function
- Subglottic hemangioma
- Tracheomalacia
- Infectious causes:
- Bacterial tracheitis
- Epiglottitis
- Viral croup
- Peritonsillar abscess
- Retropharyngeal abscess
- Supraglottitis
- Uvulitis
- Ludwig angina
- Diphtheria
- Tetanus
- COVID-19 laryngotracheitis
- Inflammatory and autoimmune causes:
- Recurrent respiratory papillomatosis
- Granulomatosis with polyangiitis
- Relapsing polychondritis
- Sarcoidosis
- Eosinophilic granulomatosis with polyangiitis
- Extrinsic compression causes:
- Hematoma
- Neck trauma
- Enlarged lymph nodes
- Mediastinal mass
- Thyroid masses/carcinomas
- Cervical vertebral abnormalities
- Mechanical obstruction (intraluminal):
- Foreign body aspiration
- Intraluminal tumors:
- Squamous cell carcinoma
- Lymphomas
- Laryngeal or tracheal papilloma
- Subglottic stenosis:
- Congenital
- Postoperative scarring
- After radiation therapy
- After prolonged endotracheal intubation
- Vocal cord dysfunction (pediatric and adult):
- Congenital vocal cord dysfunction
- Paradoxical vocal fold movement disorder (PVFMD)
- Postintubation trauma
- Surgical injury (eg, thyroidectomy)
- Neurogenic causes (stroke, Parkinson, multiple system atrophy)
- Thyroid malignancy
Adult
Adult
Adult
- Structural and mechanical causes:
- Tracheomalacia
- Postintubation subglottic stenosis
- Laryngeal or tracheal tumors
- Vocal cord paralysis
- Postsurgical trauma
- Radiation-induced laryngeal fibrosis
- Anaphylaxis and angioedema
- Tracheal stenosis from autoimmune conditions
- Extrinsic compression:
- Goiter or thyroid masses
- Mediastinal tumors
- Hematoma
- Infectious and inflammatory causes:
- Bacterial tracheitis
- Epiglottitis
- Laryngopharyngeal reflux
- Invasive fungal infections (mucormycosis in immunocompromised patients)
- Neuromuscular disorders:
- Multiple system atrophy
- Parkinson disease–related vocal cord dysfunction
- Amyotrophic lateral sclerosis
- Myasthenia gravis
There's more to see -- the rest of this topic is available only to subscribers.
© 2000–2026 Unbound Medicine, Inc. All rights reserved
All content is protected by copyright and may not be used for AI model training or other unauthorized purposes.